Results 81 to 90 of about 32,815 (232)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

Comparison between efficacy of imipramine and transcutaneous electrical nerve stimulation in the prophylaxis of chronic tension-type headache: A randomized controlled clinical trial

open access: yesJournal of Research in Medical Sciences, 2011
Background: Chronic tension-type headache (CTTH) is recognized as the most common type of headache and can be further defined as either episodic or chronic.
Sayed Ali Mousavi   +2 more
doaj  

IMIPRAMINE TREATMENT OF PANIC DISORDER PATIENTS WITH FREQUENT SLEEP PANIC

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The aim of this study was to examine the effectiveness of imipramine treatment in the panic disorder patients who had frequent sleep panic attacks as predominant clinical features.
Mehmet Yücel Ağargün   +2 more
doaj  

Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among the critical steps in MALDI–MSI workflows, matrix deposition significantly influences sensitivity, spatial
Toufik Mahamdi, Oscar Yanes
wiley   +1 more source

Effects of Voluntary Imipramine Intake via Food and Water in Paradigms of Anxiety and Depression in naïve Mice

open access: yesBrain Science Advances, 2016
Objective We sought to investigate the efficacy of oral dosing in mice with imipramine (7mg/kg/day) via water or in food pellets, and to compare its effects in the paradigms of learned helplessness, locomotion, hedonic state, and anxiety.
João Pedro Costa-Nunes   +5 more
doaj   +1 more source

Effect of Local and Application of Amitriptyline and Imipramine on Teeth with Irreversible Pulpitis Failed Pulpal Anesthesia: A Randomized, Double-blind, Controlled Trial

open access: yesDental Hypotheses, 2016
Introduction: To evaluate the analgesic effect of amitriptyline and imipramine after local application on the dentine of “hot teeth” with failed pulpal anesthesia.
Mohsen Aminsobhani   +5 more
doaj   +1 more source

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu   +4 more
wiley   +1 more source

Comparison of Lavandula officinalis tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized pilot study

open access: yesJournal of Medicinal Plants, 2002
Depression is a major health problem and is not only underrecognized and undertreated but is associated with significant morbidity and mortality. Lavandula officinalis is used to treat depression.
M Khani   +5 more
doaj  

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

open access: yesJournal of Sleep Research, Volume 35, Issue 3, June 2026.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads   +8 more
wiley   +1 more source

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