The effect of imipramine on the orthostatic changes in heart rate, blood pressure and plasma catecholamines were examined in six healthy male subjects on two occasions on high sodium balance (Na+ excretion greater than 120 mmol per day) and on low sodium
Johansen, Torben +3 more
core +1 more source
Cross-Species Triage of SERT-Oriented Polyheteroaryl Candidates Prioritizes AD20/UtIA-0108 as an Early Neuroactive Candidate. [PDF]
Komelkova MV +16 more
europepmc +1 more source
Imipramine: Do Metabolite Plasma Levels Affect Treatment Response? [PDF]
Kasanmonadi RYN +3 more
europepmc +1 more source
Long-term imipramine withdrawal induces a depressive-like behaviour in the forced swimming test
Chronic antidepressant treatments enhance dopaminergic neurotransmission in the mesolimbic dopamine system. We suggested that this potentiation might underlie both the antidepressant therapeutic effect and the antidepressant-induced switch from ...
PANIN F +2 more
core
<i>Lavandula angustifolia</i> and <i>Echium amoenum</i> as emerging adjuncts to cognitive behavioral therapy for major depressive disorder: mechanistic insights into neurotrophic, monoaminergic, and anti-inflammatory pathways. [PDF]
Song Y, Yang J, Xiao F.
europepmc +1 more source
Deacetyl xylopic acid exhibits synergistic antidepressant-like effects and augments fluoxetine activity in a chronic restraint-induced depression model in mice. [PDF]
Benneh CK +8 more
europepmc +1 more source
Dual targeting of SLC6A14 and autophagy/macropinocytosis enhances therapeutic efficacy in pancreatic ductal adenocarcinoma. [PDF]
Mahmud Syed M +9 more
europepmc +1 more source
Binding sites for the antidepressant imipramine have been described in the brain and blood platelets of several species of animals, including rats and humans.
Wilson, Marlene Ann
core
Distinct Molecular Responses to Ketamine and Imipramine in Cortical and Striatal Regions Following Acute Swim Stress. [PDF]
Begni V +7 more
europepmc +1 more source
Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats.
We studied the influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. Both single and chronic administration of imipramine potently shortened immobility in naive rats during forced-swim testing.
Kitamura, Yoshihisa +5 more
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