Results 101 to 110 of about 20,494 (215)

Cost Effectiveness of Acute Imipramine Therapy versus Two Imipramine Maintenance Treatment Regimens for Panic Disorder

Objective: To examine the medical costs and effectiveness of acute treatment with imipramine versus acute treatment plus 2 different maintenance therapies for panic disorder.
Jordana K. Schmier, Jennifer A. Flynn, Dennis A. Revicki, Matig R. Mavissakalian   +3 more
core  

A rapid and simple RP-HPLC method for quantification of desipramine in human plasma

Reviews in Analytical Chemistry, 2011
A high-performance liquid chromatographic (HPLC) method for the determination of antidepressant drug desipramine as active metabolite of imipramine in plasma is reported.
Önal Armağan, Öztunç Aysel
doaj   +1 more source

Reduced inhibitory effect of imipramine on radiolabeled serotonin uptake into platelets in geriatric depression

, 1989
Tritiated imipramine binding, uptake of radiolabeled serotonin, and inhibition of uptake by imipramine in vitro were studied in platelets obtained from four groups of subjects: 1. (1) normal controls 50 years of age or younger, 2. (2) patients with major
Slotkin, Theodore A, Barnes, Gloria A, Whitmore, William L, Nemeroff, Charles B, Knight, David L, Blazer, Dan G, Krishnan, K.Ranga R   +6 more
core   +1 more source

Modulation of neuronal serotonin uptake by a putative endogenous ligand of imipramine recognition sites

, 1983
Imipramine inhibits the serotonin uptake by binding with high affinity to regulatory sites of this uptake located on axons that release serotonin. The number of imipramine recognition sites located on crude synaptic membrane preparations is reduced by ...
Gandolfi, O, Barbaccia, ML, Costa, E, Costa, E., BARBACCIA, MARIA LUISA, Chuang, DM   +5 more
core   +1 more source

Studies of Imipramine Binding To Human Serum Albumin By High-Performance Affinity Chromatography [PDF]

, 2009
Binding by the drug imipramine to the protein human serum albumin (HSA) was studied by using high-performance affinity chromatography. The association equilibrium constants and number of binding sites for imipramine with HSA were first estimated by ...
Hage, David S., Yoo, Michelle J., Smith, Quentin R.   +2 more
core  

Regional Distribution of Imipramine, Desipramine and Specific [3H]Desipramine Binding Sites in the Rat Brain after Acute and Chronic Treatment with Imipramine

, 1991
Regional distribution of imipramine, desipramine and specific [3H]desipramine binding sites in the rat brain after acute and chronic treatment of rats with imipramine has been investigated. Both substances were distributed unevenly within rat brain after
Leokadia Danek, Lucyna Janczar, Miroslawa Melzacka, Halina Nocon, Wladyslawa Daniel   +4 more
core   +1 more source

First-pass metabolism of imipramine and desipramine: Impact of the sparteine oxidation phenotype

, 1988
Four rapid extensive metabolizers (EM), four slow EM, and three poor metabolizers (PM) of sparteine were given single intravenous doses of 50 mg imipramine and desipramine.
Kim Brøsen, Lars F Gram, Brøsen, Kim, Gram, Lars F.   +3 more
core   +1 more source

Primary enuresis and comorbid sleepwalking in an adolescent: Diagnostic and therapeutic challenges, a case report from rural Nepal

Journal of Karnali Academy of Health Sciences
Primary nocturnal enuresis (PNE) and somnambulism are categorized as arousal disorders resulting from non-rapid eye movement (NREM) sleep. These diseases have a shared neurophysiological basis: poor arousal from slow-wave sleep.
Alok Kumar Sah, Rashmi Subedi, Nabin Rawal, Jeetendra Bhandari   +3 more
doaj   +1 more source

Effect of imipramine treatment on forced swimming.

, 2013
Immobility time of Pdlim5 hetero KO and wild-type mice in the forced swimming test with saline or chronic imipramine administration.
Hiroki Ishiguro (40697), Maya Ishikawa (400588), Yasue Horiuchi (142546), Yoshimi Iijima (400590), Yoshiko Tanabe (400591), Nobuko Kaito (400589), Tadao Arinami (40713)   +6 more
core   +1 more source

Motor Performance in Hyperactive Children Treated with Imipramine

, 1988
The effects of the tricyclic antidepressant imipramine were evaluated in a study of 9 children with Attention Deficit-Hyperactivity Disorder. The study was double-blind, placebo-controlled, with three drug conditions, low, medium, and high doses.
C. Thomas Gualtieri, Randall W. Evans
core   +1 more source