Results 111 to 120 of about 49,920 (311)

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1988
The effect of various drugs on the extracellular concentration of dopamine in two terminal dopaminergic areas, the nucleus accumbens septi (a limbic area) and the dorsal caudate nucleus (a subcortical motor area), was studied in freely moving rats by ...
G. Dichiara, A. Imperato
semanticscholar   +1 more source

The relative toxicity of medicines detected after poisoning suicide deaths in Australia, 2013–19: a data linkage case series study

open access: yesMedical Journal of Australia, Volume 222, Issue 7, Page 339-347, April 2025.
Abstract Objective To compare the toxicity (relative to population use) and lethality (relative to poisoning events) of medicines involved in poisoning suicides in Australia; to determine the proportions of cases in which the medicines had recently been dispensed to the deceased person.
Jessy Lim   +6 more
wiley   +1 more source

A truly knotless technique for scleral fixation of intraocular lenses: Two-year results

open access: yesIndian Journal of Ophthalmology, 2012
Scleral fixated intraocular lens (SFIOL) is a safe and effective option for managing optical aphakia. Suture related complications like suture erosion, suture breakage, endophthalmitis, etc. are unique to SFIOL.
Naresh K Yadav   +3 more
doaj   +1 more source

The effect of different antidepressant drugs of oxidative stress after lipopolysaccharide administration in mice [PDF]

open access: yes, 2012
This study investigated the effect of the serotonin selective reuptake inhibitors (SSRIs) fluoxetine, sertraline, fluvoxamine and the tricyclic antidepressant (TCA) impiramine on oxi-dative stress in brain and liver induced by lipopolysaccharide ...
Abdel-Salam, Omar M.E.   +2 more
core  

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

open access: yes, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María   +4 more
core   +4 more sources

A randomized controlled trial of imipramine in patients with irritable bowel syndrome.

open access: yesWorld Journal of Gastroenterology, 2009
AIM To study the efficacy of low-dose imipramine in relieving symptoms associated with the irritable bowel syndrome (IBS). METHODS A randomized, double-blind trial of 25 mg imipramine vs matched placebo for 12 wk was performed.
Heitham Abdul‐Baki   +7 more
semanticscholar   +1 more source

8-Cyclopentyl-1,3-dimethylxanthine enhances effectiveness of antidepressant in behavioral tests and modulates redox balance in the cerebral cortex of mice

open access: yesSaudi Pharmaceutical Journal, 2018
The objective of our study was to investigate whether 8-cyclopentyl-1,3-dimethylxanthine (CPT), associated with the adenosine system, enhances the antidepressant efficacy of antidepressant. All experiments were carried out on Albino Swiss mice. Following
Mariola Herbet   +9 more
doaj  

Inhibiting extracellular vesicles formation and release: a review of EV inhibitors

open access: yesJournal of Extracellular Vesicles, 2020
It is now becoming well established that vesicles are released from a broad range of cell types and are involved in cell-to-cell communication, both in physiological and pathological conditions.
Mariadelva Catalano   +1 more
doaj   +1 more source

A Comparative Survey of the Effects of Fluoxetine and Imipramine on Depression-Like Behavior and Serum Levels of Corticosterone and Glucose in Male Rats under Immobilization Stress

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: Depression is one of the most common psychiatric disorders, which can be detected and continued through stressful life events.
Razieh Bayramlou   +2 more
doaj  

The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]

open access: yes, 2011
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman   +8 more
core   +1 more source

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