A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression [PDF]
Advanced ScienceSepsis is characterized by the simultaneous presence of hyperinflammation, immunosuppression, and coagulation abnormalities, making single‐target therapies insufficient.
Yi Zhou +11 more
doaj +3 more sources
IrMn-Cluster-Based Artificial Metalloenzymes with Radiosensitized Systemic Antitumor Responses to Prevent Malignant Tumor Metastasis and Recurrence [PDF]
Nano-Micro LettersHighlights The bioinspired design of IrMn-based redox centers (IMM) with rapid electron transfer can promote the formation of electron-rich IMM, thereby guaranteeing superior radio-enhanced reactive oxygen species biocatalysis and O2 generation.
Ruidan Li +10 more
doaj +2 more sources
Infiltrating monocyte-derived macrophages does not survive long term in stroke brain despite their dominance in the acute ischemic core and myeloid derived IGF-1 play dichotomous roles in stroke recovery [PDF]
Genome MedicineBackground Ischemic stroke elicits a strong neuroinflammatory response characterized by activation of microglia and infiltration of monocytes-derived macrophages (iMM), which have been speculated to have differential functions in stroke. However, because
Hongli Ma +7 more
doaj +2 more sources
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta. [PDF]
Clin Pharmacol TherSolute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Jung EM +12 more
europepmc +2 more sources
Variable- and Fixed-Structure Augmented IMM Algorithms Using Coordinated Turn Model [PDF]
, 2000 A new variable-structure (VS) Augmented Interacting Multiple Model (AIMM) technique is developed in the paper. Fixed-structure (FS) and VS AIMM algorithms using augmented constant velocity and augmented coordinated turn (ACT) models, are proposed.
Semerdjiev, E. +2 more
core +4 more sources
Beyond Bioenergetics: Moonlighting Functions of F<sub>1</sub>F<sub>O</sub>-ATPase From ATP Synthesis to an ATP-Wasting Death Switch. [PDF]
Med Res RevABSTRACT Mitochondrial F1FO‐ATPase is classically viewed as the “splendid” rotary nanomachine that sustains life by converting the proton‐motive force (pmf) into ATP. Yet this same complex can adopt a second, context‐dependent function that links bioenergetics to cell fate.
Nesci S.
europepmc +2 more sources
State estimation by IMM filter in the presence of structural uncertainty [PDF]
, 1999 A solution to the state estimation problem under structural uncertainty (unknown or changeable dimension of the system state space) is given by the Interacting Multiple Model (IMM) filter.
Mihaylova, L.
core +4 more sources
ACCURACY IMPROVEMENT OF A IMMS IN AN URBAN SCENARIO [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2022 Abstract. Indoor Mobile Mapping Systems (IMMSs) technologies are becoming increasingly popular thanks to the possibility of acquiring a massive amount of 3D data in a fast and effective way in those areas where GNSS signal is unavailable, like urban canyons, densely vegetated areas, underground sites and buildings.
Marotta F. +3 more
openaire +3 more sources
Identification of Hysteresis Functions Using a Multiple Model Approach [PDF]
, 2001 This paper considers the identification of static hysteresis functions which describe phenomena in mechanical systems, piezoelectric actuators and materials.
Mihaylova, L +3 more
core +4 more sources
IEEE Access, 2022 This paper proposes a novel state estimation algorithm, called the distributed Frobenius-norm finite memory interacting multiple model (DFFM-IMM) estimation algorithm, for mobile robot localization in wireless sensor networks (WSNs).
Duckhyun Suh +3 more
doaj +1 more source