Results 51 to 60 of about 25,718 (199)

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

IMM-SUPF for Maneuvering Area Target Tracking Based on Fuzzed Model Probability

工程科学与技术, 2017
:In order to improve the tracking ability of the surface maneuvering target,the surface target was modeled as an elliptical area,and an interacting multiple model (IMM) strong unscented particle filter based on fuzzed model probability was proposed ...
石杰, 李银伢, 戚国庆, 盛安冬
doaj  

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

Advanced Science, EarlyView.
A solvation‐guided design strategy for electrolyte additives is established, identifying Li‐ion binding energy as a crucial determinant for effective interface reinforcement. ABSTRACT The rational design of electrolyte systems is essential for stabilizing the electrode−electrolyte interface to enhance the electrochemical performance of lithium‐ion ...
Jooeun Byun, Ho Yeon Jang, Myung‐Jun Kwak, Chae Rim Lee, Chihyun Hwang, Seoin Back, Hyun‐seung Kim   +6 more
wiley   +1 more source

InGaP/GaAs/InGaAs Multijunction Flexible Photovoltaics With Chemical Robustness and Radiation Hardness for Unassisted Electrocatalysis and Space Applications

Advanced Energy Materials, EarlyView.
A flexible InGaP/GaAs/InGaAs triple‐junction platform encapsulated with ultrathin glass enables unassisted electrocatalysis and space applications by providing robust protection against chemically aggressive and radiation‐rich environments. This work establishes a unified III–V multijunction photovoltaic platform that bridges space photovoltaics and ...
Sukkyu Hong, Seungwan Woo, Hoki Son, Hyun‐Beom Shin, Eungbeom Yeon, Jeongeun Mo, Daehwan Jung, Ho Won Jang, Ho Kwan Kang, Sung‐Min Lee, Won Jun Choi   +10 more
wiley   +1 more source

La creación de las Instancias Municipales de la Mujer en Chihuahua 2000-2014

Chihuahua Hoy, 2018
El documento describe la creación e instauración de las Instancias Municipales de las Mujeres (IMM) principal mecanismo institucional para generar e instrumentar políticas públicas para el adelanto de las mujeres en el estado de Chihuahua durante el ...
Martha Cecilia Miker Palafox, Cecilia Sarabia Rios   +1 more
doaj   +1 more source

Physics‐Grounded Probabilistic Bits for Hardware‐Efficient Intelligent Inference and Optimization

Advanced Intelligent Systems, EarlyView.
Si–SiNx interface traps are harnessed as a complementary metal–oxide–semiconductor‐compatible source of controllable randomness for probabilistic bits. Pulse‐width‐programmed stochastic capture converts nanoscale defect dynamics into Boltzmann‐consistent binary outputs, while a physics‐based Simulation Program with Integrated Circuit Emphasis model ...
Dokyoung Lee, Jun‐Young Park, Joon‐Kyu Han, Sungho Kim   +3 more
wiley   +1 more source

IMM COLOGNE 2008

Drvna industrija, 2007
IMM Cologne, najpoznatiji i najveći sajam namještaja i unutarnjeg uređenja u Europi, otvorio je svoja vrata izlagačimai posjetiteljima od 14. do 20. siječnja 2008. godine. U ovom radu prikazani su najnoviji trendovi u području unutarnjeg uređenja i dizajnu namještaja koji su bili prikazani u sklopu sajma IMM Cologne uz pregled popratnih događanja u ...
Grbac, Ivica, Ojurović, Renata, Gašparić, Vanja   +2 more
openaire   +2 more sources

IMM‐H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high‐fat diet

FEBS Open Bio, 2017
Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease in humans, is characterized by the accumulation of triacylglycerols (TGs) in hepatocytes.
Huijie Shi, Qingchun Wang, Liu Yang, Shouxia Xie, Haibo Zhu   +4 more
doaj   +1 more source

Parliamentary Imm(p)unity

Procedia Economics and Finance, 2015
AbstractThe parliamentary immunity as an ensemble of legal provisions, ensures for the deputies and the senators a derogatory juridical system from the common law, in relation to the justice and with the purpose of guaranteeing their independence. The protection that is being offered to the members of the Parliament against potential abuses from the ...
Onofrei, Mihaela, Gradinaru, Sandra
openaire   +1 more source