Results 51 to 60 of about 41,720 (270)

A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

open access: yesSkeletal Muscle, 2018
Background The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofibers. The purpose of this study was
Carrie J. Finno   +9 more
doaj   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

Echocardiography interpretation training and internal medicine milestones: A pilot study

open access: yesJournal of the Formosan Medical Association
Background/Purpose: The competency-based Internal Medicine Milestones (IMM) assesses physician training outcomes through six key competencies. This pilot study introduced IMM concepts through an echocardiography report interpretation course for ...
Li-Tan Yang   +4 more
doaj   +1 more source

Improving Treatment of Noise Specification of Kalman Filtering for State Updating of Hydrological Models: Combining the Strengths of the Interacting Multiple Model Method and Cubature Kalman Filter

open access: yesWater Resources Research, 2023
Filtering methods have been widely used to improve the forecast performances of hydrological models. Although extensive research has been carried out on filtering methods in the hydrology literature, researchers have not treated the noise statistics of ...
Y. Sun   +7 more
doaj   +1 more source

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

open access: yesAdvanced Science, EarlyView.
A solvation‐guided design strategy for electrolyte additives is established, identifying Li‐ion binding energy as a crucial determinant for effective interface reinforcement. ABSTRACT The rational design of electrolyte systems is essential for stabilizing the electrode−electrolyte interface to enhance the electrochemical performance of lithium‐ion ...
Jooeun Byun   +6 more
wiley   +1 more source

HY - IMM [PDF]

open access: yes
OnLine Card Catalogue drawer 0200 (HY - IMM).
Craft, Edward
core   +5 more sources

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Modeling as Story-Building and Storytelling: Developing the Mathematical Identities of Adolescent Girls of Color

open access: yesJournal of Mathematics Education at Teachers College, 2021
“Algebra-as-gatekeeper” is a powerful paradigm that structures students’ experiences within mathematics class, as well as their future educational trajectories.
Kara Imm
doaj  

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

open access: yesAdvanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui   +12 more
wiley   +1 more source

Interfacial Interaction‐Engineered Dual Lithiophilic Ultrathin Interlayers for Dendrite‐Suppressed Lithium Metal Textile Anodes

open access: yesAdvanced Science, EarlyView.
Ultrathin lithiophilic interlayers engineered on a 3D textile electrode and separator cooperatively regulate interfacial Li nucleation and Li+ transport, leading to homogeneous Li plating and mitigated dendrite formation. The resulting dual‐interfacial design provides long‐term cycling stability, improved full‐cell durability, and a scalable pathway ...
Chanseok Lee   +12 more
wiley   +1 more source

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