Results 41 to 50 of about 238,521 (253)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Strategic male mating effort and cryptic male choice in a scorpionfly [PDF]

open access: yes, 2001
Engqvist L, Sauer KP. Strategic male mating effort and cryptic male choice in a scorpionfly. Proceedings of the Royal Society B. 2001;268(1468):729-735.In animal species with high male mating effort, males often find themselves in a dilemma: by ...
Sauer, Klaus Peter   +1 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Reproductive biology of Sympterygia bonapartii (Chondrichthyes: Rajiformes: Arhynchobatidae) in San Matías Gulf, Patagonia, Argentina

open access: yesNeotropical Ichthyology, 2017
This study estimates and analyses the reproductive parameters and cycle of Sympterygia bonapartii in San Matías Gulf, northern Patagonia, Argentina. A total of 827 males and 1,299 females were analysed. Males ranged from 185 to 687 mm of total length (TL)
María L. Estalles   +2 more
doaj   +1 more source

Non-random mating for selection with restricted rates of inbreeding and overlapping generations [PDF]

open access: yes, 2002
Minimum coancestry mating with a maximum of one offspring per mating pair (MC1) is compared with random mating schemes for populations with overlapping generations. Optimum contribution selection is used, whereby ΔF is restricted.
Anna K Sonesson   +9 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic Basis of Self-Incompatibility in the Lichen-Forming Fungus Lobaria pulmonaria and Skewed Frequency Distribution of Mating-Type Idiomorphs: Implications for Conservation [PDF]

open access: yes, 2012
Fungal populations that reproduce sexually are likely to be genetically more diverse and have a higher adaptive potential than asexually reproducing populations.
Dal Grande, Francesco   +14 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Effects of Fluctuating Thermal Regimes on Life History Parameters and Body Size of Ophraella communa

open access: yesInsects, 2022
The beetle Ophraella communa is an effective biological control agent against the invasive common ragweed spread across various ecosystems with variable temperature ranges.
Chenchen Zhao   +3 more
doaj   +1 more source

Sex, food and conflicts: nutrition dependent nuptial feeding and pre-mating struggles in scorpionflies [PDF]

open access: yes, 2007
Engqvist L. Sex, food and conflicts: nutrition dependent nuptial feeding and pre-mating struggles in scorpionflies. Behavioral Ecology and Sociobiology. 2007;61(5):703-710.Female and male reproductive interests often differ.
Engqvist, Leif ; https://orcid.org/
core   +1 more source

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