Results 61 to 70 of about 18,588 (258)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A method for single pair mating in an obligate parasitic nematode [PDF]

, 2017
Parasitic nematodes species have extremely high levels of genetic diversity, presenting a number of experimental challenges for genomic and genetic work.
Elizabeth Redman, Bartley, David J., Bartley, David Jon, Nancy Holroyd, Sargison, Neil, David J. Bartley, Morrison, Alison A., Berriman, Matthew, Morrison, Alison, Alison A. Morrison, Cotton, James A., Jackson, Frank, Gilleard, J S, Frank Jackson, Sargison, Neil D., Neil D. Sargison, Holroyd, Nancy E., Redman, Elizabeth, James A. Cotton, Gilleard, John S., Naghra-van Gijzel, Hardeep, Cotton, James, Hardeep Naghra-van Gijzel, Matthew Berriman, Holroyd, Nancy, Naghra, Hardeep, John S. Gilleard   +26 more
core   +1 more source

Immature and mating behavior of Neocompsa alacris (Bates) (Coleoptera: Cerambycidae)

, 1966
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Growth and reproduction in harbour porpoises (Phocoena phocoena) in Icelandic waters

NAMMCO Scientific Publications, 2003
A total of 1,268 harbour porpoises were obtained from fishing nets in Icelandic coastal waters from September to June in the years 1991 to 1997. Foetal sex ratio was 1.2:1 (male:female). The bias towards males increased further among older animals in the
Droplaug Ólafsdóttir, Gísli A Víkingsson, Sverrir Daníel Halldórsson, Jóhann Sigurjónsson   +3 more
doaj   +1 more source

Ejaculate economics: testing the effects of male sexual history on the trade-off between sperm and immune function in Australian crickets. [PDF]

PLoS ONE, 2012
Trade-offs between investment into male sexual traits and immune function provide the foundation for some of the most prominent models of sexual selection. Post-copulatory sexual selection on the male ejaculate is intense, and therefore trade-offs should
Damian K Dowling, Leigh W Simmons
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Nature beats nurture: a case study of the physiological fitness of free-living and laboratory-reared male Anopheles gambiae s.l. [PDF]

, 2007
Laboratory experimentation forms the basis for most of our knowledge of the biology of many organisms, in particular insects. However, the accuracy with which laboratory-derived estimates of insect life history and behaviour can predict their fitness and
Killeen, G.F., Ng’habi, K.R., Knols, B.G.J., Knols, B G J, Ferguson, H.M., Nkwengulila, G, Ng'habi, K R, Nghabi, K.R., Huho, B.J., H. M. Ferguson, B. J. Huho, Ferguson, H M, Huho, B J, Hubo, B.J., G. F. Killeen, G. Nkwengulila, Nkwengulila, G., Killeen, G F, K. R. Ng'habi, Ng'habi, K.R., B. G. J. Knols   +20 more
core   +1 more source