Results 1 to 10 of about 896,074 (380)

Time course of immediate early gene protein expression in the spinal cord following conditioning stimulation of the sciatic nerve in rats. [PDF]

PLoS ONE, 2015
Long-term potentiation induced by conditioning electrical stimulation of afferent fibers is a widely studied form of synaptic plasticity in the brain and the spinal cord.
Ognjen Bojovic, Debabrata Panja, Margarethe Bittins, Clive R Bramham, Arne Tjølsen   +4 more
doaj   +1 more source

Characteristics of Immediate-Early 2 (IE2) and UL84 Proteins in UL84-Independent Strains of Human Cytomegalovirus (HCMV)

Microbiology Spectrum, 2021
Human cytomegalovirus (HCMV) immediate-early 2 (IE2) protein is the major transactivator for viral gene expression and is required for lytic replication.
Salome Manska, Cyprian C. Rossetto
doaj   +1 more source

The immediate early gene product EGR1 and polycomb group proteins interact in epigenetic programming during chondrogenesis. [PDF]

PLoS ONE, 2013
Initiation of and progression through chondrogenesis is driven by changes in the cellular microenvironment. At the onset of chondrogenesis, resting mesenchymal stem cells are mobilized in vivo and a complex, step-wise chondrogenic differentiation program
Frank Spaapen, Guus G H van den Akker, Marjolein M J Caron, Peggy Prickaerts, Celine Rofel, Vivian E H Dahlmans, Don A M Surtel, Yvette Paulis, Finja Schweizer, Tim J M Welting, Lars M Eijssen, Jan Willem Voncken   +11 more
doaj   +1 more source

Detection of Human Cytomegalovirus in Atherosclerotic Carotid Arteries in Humans

Journal of the Formosan Medical Association, 2008
Atherosclerosis plays an important role in stroke. A microbiological infection has been suggested to be involved in the pathogenesis of atherosclerosis, in particular the human cytomegalovirus (HCMV).
Li Yi, De-Xin Wang, Zi-Jing Feng
doaj   +1 more source

Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis.

Carcinogenesis, 2014
A lack of gap junctional intercellular communication (GJIC) is common in cancer. Many oncogenic viruses have been shown to downregulate the junctional protein connexin 43 (Cx43) and reduce GJIC.
Z. Khan, Koon-Chu Yaiw, Vanessa Wilhelmi, Hoyin Lam, A. Rahbar, G. Stragliotto, C. Söderberg-Nauclér   +6 more
semanticscholar   +1 more source

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling, AB Rickinson, ARM Townsend, ARM Townsend, B Roizman, BT Rouse, C Taswell, deSt Fazekas, DR Mayo, G Berke, GM Keil, GV Quinnan, JB Hudson, JD Meyers, JD Shanley, JE Grundy, JK Chantler, JR Bennink, JR Marks, LK Borysiewicz, LR Gooding, M Ho, Matthias J. Reddehase, MC Jordan, MF Stinski, MJ Bevan, MJ Imperiale, MJ Reddehase, MJ Reddehase, MR Green, PG Spear, RJ Watson, RM Stenberg, RW Honess, SS Tevethia, UH Koszinowski, Ulrich H. Koszinowski   +36 more
core   +1 more source

Establishment of an indirect ELISA method for detection of human cytomegalovirus [PDF]

精准医学杂志
Objective To establish an indirect ELISA method for the detection of human cytomegalovirus (HCMV) based on HCMV IE1/pp65/pp150 recombinant protein. Methods From June to December 2024, 5 serum samples from HCMV IgG-positive patients, 50 serum samples from
LI Xu, WANG Shan, HUANG Huan, WANG Bin, QIAN Dongmeng
doaj   +1 more source

Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers.

PLoS Pathogens, 2021
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the ...
Johannes Schweininger, Myriam Scherer, Franziska Rothemund, Eva-Maria Schilling, Sonja Wörz, Thomas Stamminger, Yves A Muller   +6 more
doaj   +1 more source

Intranuclear localization of herpes simplex virus immediate-early and delayed-early proteins: evidence that ICP 4 is associated with progeny virus DNA.

Journal of General Virology, 1986
The localization of ICP 4, ICP 8, DNA polymerase and alkaline exonuclease within herpes simplex virus type 1 (HSV)-infected cells has been examined by immunofluorescence using specific antibodies to these proteins.
R. Randall, N. Dinwoodie
semanticscholar   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J., Engelsma, M.Y., Peeters, B.P.H., Rottier, P.J.M., van Beurden, S.J.   +4 more
core   +3 more sources