Results 141 to 150 of about 891,156 (376)

The Transcriptional Corepressor NAB2 Inhibits NGF-induced Differentiation of PC12 Cells [PDF]

, 1998
The PC12 pheochromocytoma cell line responds to NGF by undergoing growth arrest and proceeding to differentiate toward a neuronal phenotype. Among the early genetic events triggered by NGF in PC12 cells are the rapid activation of the zinc finger ...
Davidson, Norman, Ehrengruber, Markus U., Milbrandt, Jeffrey, Qu, Zhican, Svaren, John, Wolfraim, Lawrence A.   +5 more
core   +2 more sources

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

Advanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari, Sanchyan Bhowmik, Kaiwen Zhang, Chayla L. Reeves, Danielle Vahala, Yu Suk Choi, Amy Gelmi, Alexander N. Combes, Rocky S. Tuan, Vinh X. Truong, John S. Forsythe, Jessica E. Frith   +11 more
wiley   +1 more source

Effect of human cytomegalovirus immediate-early protein 2 on hepatic steatosis induced by fructose in UL122 transgenic model mice [PDF]

精准医学杂志
Objective To investigate the effect of human cytomegalovirus immediate-early protein 2 (HCMV-IE2) on fructose-induced hepatic steatosis in UL122 transgenic model mice.
ZHOU Xiaoqiong, ZHANG Xianjuan, WANG Bin
doaj   +1 more source

Kaposi's Sarcoma-Associated Herpesvirus Immediate Early Proteins Trigger FOXQ1 Expression in Oral Epithelial Cells, Engaging in a Novel Lytic Cycle-Sustaining Positive Feedback Loop. [PDF]

J Virol, 2023
Atyeo N, Chae MY, Toth Z, Sharma A, Papp B.   +4 more
europepmc   +1 more source

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]

, 1991
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Braciale, Chimini, Colbere-Garapin, Del Val, Del Val, Del Val, DeLisi, Falk, Falk, Ganem, Hans-Jürgen Schlicht, Jonjić, Junker, Keil, Margarita Del Val, Matthias J. Reddehase, Nassal, Ou, Parham, Ponta, Reddehase, Reddehase, Rothbard, Rötzschke, Rötzschke, Schlicht, Schlicht, Thomas Ruppert, Townsend, Townsend, Townsend, Townsend, Townsend, Ulrich H. Koszinowski, Van Bleek, Volkmer, Yewdell   +36 more
core   +1 more source

Eco‐Fabricated Nanowave‐Textured Implants Drive Microtubule‐Assisted Nuclear Mechanotransduction and Chromatin Modification: Biophysical Priming for Osteogenesis and Bone Regeneration

Advanced Functional Materials, EarlyView.
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong, Ji‐Young Yoon, Junyong Ahn, Byunghak Lee, Sung‐Min Park, Jae‐Heon Kim, Buuvee Bayarkhangai, Yu Jin Kim, Sak Lee, Jonathan C. Knowles, Moon‐Young Kim, DongJun Lee, Sang‐Hoon Rhee, Hae‐Hyoung Lee, Hae‐Won Kim, Jung‐Hwan Lee   +15 more
wiley   +1 more source

Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP. [PDF]

Int J Mol Sci, 2022
Hong YM, Min SY, Kim D, Kim S, Seo D, Lee KH, Han SH.   +6 more
europepmc   +1 more source

Early post parturient changes in milk acute phase proteins [PDF]

, 2016
The periparturient period is one of the most critical periods in the productive life of a dairy cow, and is the period when dairy cows are most susceptible to developing new intramammary infections (IMI) leading to mastitis.
Eckersall, Peter, Haining, Hayley, Hastie, Peter, Thomas, Funmilola C., Waterston, Mary   +4 more
core   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

Poly (A) binding protein 2 is critical for stem cell differentiation during regeneration in the planarian Schmidtea mediterranea

Frontiers in Cell and Developmental Biology
Post-transcriptional regulation has emerged as a key mechanism for regulating stem cell renewal and differentiation, which is essential for understanding tissue regeneration and homeostasis.
Namita Mukundan, Namita Mukundan, Nivedita Hariharan, Vidyanand Sasidharan, Vairavan Lakshmanan, Dasaradhi Palakodeti, Dasaradhi Palakodeti, Colin Jamora, Colin Jamora   +8 more
doaj   +1 more source