This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao +8 more
wiley +1 more source
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Rapid Membrane Effects of Steroids in Neuroblastoma Cells: Effects of Estrogen on Mitogen Activated Protein Kinase Signalling Cascade and c-fos Immediate Early Gene Transcription [PDF]
Jyoti J. Watters +4 more
openalex +1 more source
A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova +5 more
wiley +1 more source
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello +2 more
wiley +1 more source
The DNA repair associated protein Gadd45 γ regulates the temporal coding of immediate early gene expression and is required for the consolidation of associative fear memory [PDF]
Xiang Li +5 more
openalex +1 more source
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach +7 more
wiley +1 more source
Analysis of human cytomegalovirus-encoded SUMO targets and temporal regulation of SUMOylation of the immediate-early proteins IE1 and IE2 during infection. [PDF]
Kim ET +5 more
europepmc +1 more source
The Human Analog of Murine Cystein Rich Protein 16 Is a 1α,25-Dihydroxyvitamin D3 Responsive Immediate Early Gene in Human Fetal Osteoblasts: Regulation by Cytokines, Growth Factors, and Serum* [PDF]
Norbert Schütze +6 more
openalex +1 more source

