Results 251 to 260 of about 888,744 (374)

Resting Ca<sup>2+</sup> fluxes protect cells from fast mitochondrial fragmentation, cell stress responses, and immediate transcriptional reprogramming. [PDF]

open access: yesCell Mol Life Sci
Fecher C   +9 more
europepmc   +1 more source

Gamma‐Glutamyl Cysteine Ligase Activity as a Proxy for Human T Cell Function and Drug‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
GLed, a reversible lanthanide‐based GSH sensor that enables real‐time, single‐cell measurement of Gamma–Glutamyl Cysteine Ligase (GCL) activity ‐whose role in human T cells remains unclear‐ is developed. GLed directly links GCL activity to T cell effector functions and reveals its modulation by immunosuppressive drugs, identifying GCL as a critical ...
Francisco Fueyo‐González   +9 more
wiley   +1 more source

<i>Pseudorabies Virus</i> IE180 Inhibits Virus Replication by Activating the Type I Interferon Pathway. [PDF]

open access: yesMicroorganisms
Zheng F   +7 more
europepmc   +1 more source

Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

open access: yesAdvanced Science, EarlyView.
The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia   +12 more
wiley   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

open access: yesAdvanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie   +8 more
wiley   +1 more source

Human Cytomegalovirus Immediate-Early Protein IE2–86, but not IE1–72, Causes Graft Coronary Arteriopathy in the Transplanted Rat Heart [PDF]

open access: bronze, 2002
Ken Suzuki   +5 more
openalex   +1 more source

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