Results 21 to 30 of about 480,670 (335)

Detection of Human Cytomegalovirus in Atherosclerotic Carotid Arteries in Humans

Journal of the Formosan Medical Association, 2008
Atherosclerosis plays an important role in stroke. A microbiological infection has been suggested to be involved in the pathogenesis of atherosclerosis, in particular the human cytomegalovirus (HCMV).
Li Yi, De-Xin Wang, Zi-Jing Feng
doaj   +1 more source

The immediate early gene product EGR1 and polycomb group proteins interact in epigenetic programming during chondrogenesis. [PDF]

PLoS ONE, 2013
Initiation of and progression through chondrogenesis is driven by changes in the cellular microenvironment. At the onset of chondrogenesis, resting mesenchymal stem cells are mobilized in vivo and a complex, step-wise chondrogenic differentiation program
Frank Spaapen, Guus G H van den Akker, Marjolein M J Caron, Peggy Prickaerts, Celine Rofel, Vivian E H Dahlmans, Don A M Surtel, Yvette Paulis, Finja Schweizer, Tim J M Welting, Lars M Eijssen, Jan Willem Voncken   +11 more
doaj   +1 more source

Role of Human Cytomegalovirus Immediate-Early Proteins in Cell Growth Control [PDF]

Journal of Virology, 2000
ABSTRACT Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that has been implicated in several disorders, including an association between HCMV reactivation and the overproliferation of arterial smooth muscle cells observed in restenosis.
Castillo, Jonathan Patrick, Yurochko, Andrew D., Kowalik, Timothy F.   +2 more
openaire   +3 more sources

Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers.

PLoS Pathogens, 2021
Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the ...
Johannes Schweininger, Myriam Scherer, Franziska Rothemund, Eva-Maria Schilling, Sonja Wörz, Thomas Stamminger, Yves A Muller   +6 more
doaj   +1 more source

Establishment of an indirect ELISA method for detection of human cytomegalovirus [PDF]

精准医学杂志
Objective To establish an indirect ELISA method for the detection of human cytomegalovirus (HCMV) based on HCMV IE1/pp65/pp150 recombinant protein. Methods From June to December 2024, 5 serum samples from HCMV IgG-positive patients, 50 serum samples from
LI Xu, WANG Shan, HUANG Huan, WANG Bin, QIAN Dongmeng
doaj   +1 more source

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling, AB Rickinson, ARM Townsend, ARM Townsend, B Roizman, BT Rouse, C Taswell, deSt Fazekas, DR Mayo, G Berke, GM Keil, GV Quinnan, JB Hudson, JD Meyers, JD Shanley, JE Grundy, JK Chantler, JR Bennink, JR Marks, LK Borysiewicz, LR Gooding, M Ho, Matthias J. Reddehase, MC Jordan, MF Stinski, MJ Bevan, MJ Imperiale, MJ Reddehase, MJ Reddehase, MR Green, PG Spear, RJ Watson, RM Stenberg, RW Honess, SS Tevethia, UH Koszinowski, Ulrich H. Koszinowski   +36 more
core   +1 more source

Revisiting promyelocytic leukemia protein targeting by human cytomegalovirus immediate-early protein 1

PLOS Pathogens, 2020
Promyelocytic leukemia (PML) bodies are nuclear organelles implicated in intrinsic and innate antiviral defense. The eponymous PML proteins, central to the self-organization of PML bodies, and other restriction factors found in these organelles are common targets of viral antagonism.
Christina Paulus, Thomas Harwardt, Bernadette Walter, Andrea Marxreiter, Marion Zenger, Edith Reuschel, Michael M. Nevels   +6 more
openaire   +6 more sources

The metabotropic P2Y4 receptor participates in the commitment to differentiation and cell death of human neuroblastoma SH-SY5Y cells

Neurobiology of Disease, 2005
Extracellular nucleotides exert a variety of biological actions through different subtypes of P2 receptors. Here we characterized in the human neuroblastoma SH-SY5Y cells the simultaneous presence of various P2 receptors, belonging to the P2X ionotropic ...
Fabio Cavaliere, Valeria Nestola, Susanna Amadio, Nadia D'Ambrosi, Daniela F. Angelini, Giuseppe Sancesario, Giorgio Bernardi, Cinzia Volonté   +7 more
doaj   +1 more source

The cytolytic T lymphocyte response to the murine cytomegalovirus [PDF]

, 1984
During the acute cytolytic T lymphocyte (CTL) response of mice to infection with the murine cytomegalovirus two independent populations of activated interleukin-receptive CTL precursors can be demonstrated.
Ada, Beyer, Chantler, Costanzo, Ebeling, Honess, Hudson, Jackson, Kendall, Kim, Koszinowski, Koszinowski, Laemmli, Mulligan, Osborn, Pfizenmaier, Reddehase, Robinson, Sethi, Sethi, Spear, Svedmyr, Ueda, Zinkernagel, Zinkernagel, Zinkernagel   +25 more
core   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J., Engelsma, M.Y., Peeters, B.P.H., Rottier, P.J.M., van Beurden, S.J.   +4 more
core   +3 more sources