Results 51 to 60 of about 480,670 (335)

Identifying the key regulators orchestrating Epstein-Barr virus reactivation

Frontiers in Microbiology
Epstein-Barr virus (EBV) infects more than 90% of the human population worldwide and establishes lifelong infection in hosts by switching between latent and lytic infection.
Yaohao Wang, Jingwen Yu, Yonggang Pei
doaj   +1 more source

Identification of Cellular Proteins that Interact with Human Cytomegalovirus Immediate-Early Protein 1 by Protein Array Assay

Viruses, 2013
Human cytomegalovirus (HCMV) gene expression during infection is characterized as a sequential process including immediate-early (IE), early (E), and late (L)-stage gene expression.
Francisco Puerta Martínez, Qiyi Tang
doaj   +1 more source

Infection of human cytomegalovirus in cultured human gingival tissue. [PDF]

, 2006
BackgroundHuman cytomegalovirus (HCMV) infection in the oral cavity plays an important role in its horizontal transmission and in causing viral-associated oral diseases such as gingivitis.
Chu, Alice, Hai, Rong, Li, Hongjian, Liu, Fenyong, Rider, Paul, Umamoto, Sean   +5 more
core   +3 more sources

MORC3, a component of PML nuclear bodies, has a role in restricting herpes simplex virus type 1 and human cytomegalovirus [PDF]

, 2016
We previously reported that MORC3, a protein associated with promyelocytic leukemia nuclear bodies (PML NBs), is a target of HSV-1 ICP0 mediated degradation.
Everett, Roger, Orr, Anne, Sloan, Elizabeth   +2 more
core   +1 more source

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein [PDF]

, 1991
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC class I molecules to CD8 T lymphocytes. Here it is documented that not only the sequence of the presented peptide but also the residues by which it is ...
Braciale, Chimini, Colbere-Garapin, Del Val, Del Val, Del Val, DeLisi, Falk, Falk, Ganem, Hans-Jürgen Schlicht, Jonjić, Junker, Keil, Margarita Del Val, Matthias J. Reddehase, Nassal, Ou, Parham, Ponta, Reddehase, Reddehase, Rothbard, Rötzschke, Rötzschke, Schlicht, Schlicht, Thomas Ruppert, Townsend, Townsend, Townsend, Townsend, Townsend, Ulrich H. Koszinowski, Van Bleek, Volkmer, Yewdell   +36 more
core   +1 more source

Mutational analysis of varicella-zoster virus major immediate-early protein IE62

Nucleic Acids Research, 1995
The varicella-zoster virus (VZV) open reading frame 62 encodes an immediate-early protein (IE62) that transactivates expression of various VZV promoters and autoregulates its own expression in transient expression assays. In Vero cells, IE62 was shown to transactivate the expression of all putative immediate-early (IE) and early (E) genes of VZV with ...
Baudoux, Laurence, Defechereux, Patricia, Schoonbroodt, Sonia, Merville, Marie-Paule, Rentier, Bernard, Piette, Jacques   +5 more
openaire   +3 more sources

Human Cytomegalovirus UL34 Early and late Proteins Are Essential for Viral Replication

Viruses, 2014
UL34 is one of the ~50 genes of human cytomegalovirus (HCMV) required for replication in cell culture in human fibroblasts. UL34 encodes highly related early (UL34a) and late (UL34b) proteins that are virtually identical, with the early protein ...
Rico Rana, Bonita J. Biegalke
doaj   +1 more source

Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor [PDF]

, 1994
We have shown previously that the antiviral function of CD4+ T lymphocytes against murine cytomegalovirus (MCMV) is associated with the release of interferon- (IFN-).
Hengel, Hartmut, Jonjic, Stipan, Koszinowski, Ulrich H., Lucin, Pero, Messerle, Martin, Polic, Bojan   +5 more
core   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Endothelin-1 Activates MAPKs and Modulates Cell Cycle Proteins in OKP Cells

Journal of the Formosan Medical Association, 2007
The signaling mechanisms through which endothelin (ET)-1 induces hyperplasia of the renal tubular epithelium are largely unknown. Methods: These mechanisms were explored using ETB-overexpressing opossum kidney (OKP) cells as a model system. Results: ET-1
Tzong-Shinn Chu, Ming-Shiou Wu, Kwan-Dun Wu, Bor-Shen Hsieh   +3 more
doaj   +1 more source