Results 201 to 210 of about 1,253,551 (390)

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Human IFIT3 Protein Induces Interferon Signaling and Inhibits Adenovirus Immediate Early Gene Expression. [PDF]

mBio, 2021
Chikhalya A, Dittmann M, Zheng Y, Sohn SY, Rice CM, Hearing P.   +5 more
europepmc   +1 more source

Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene

, 2020
Yao-Tang Lin, Stephen Chiweshe, Dominique McCormick, Anna Raper, Arthur Wickenhagen, Victor DeFillipis, Eleanor Gaunt, Peter Simmonds, Sam J. Wilson, Finn Grey   +9 more
openalex   +1 more source

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation. [PDF]

J Neurosci, 2021
Kyrke-Smith M, Volk LJ, Cooke SF, Bear MF, Huganir RL, Shepherd JD.   +5 more
europepmc   +1 more source

Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters [PDF]

, 1989
Wanda Cromlish, Susan M. Abmayr, Jerry L. Workman, M Horikoshi, Robert G. Roeder   +4 more
openalex   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Duck Plague Virus pUL48 Protein Activates the Immediate-Early Gene to Initiate the Transcription of the Virus Gene. [PDF]

Front Microbiol, 2021
Zhou T, Fan D, Wang M, Cheng A, Wu Y, Yang Q, Tian B, Jia R, Ou X, Mao S, Sun D, Zhang S, Zhu D, Chen S, Liu M, Zhao XX, Huang J, Gao Q, Yu Y, Zhang L.   +19 more
europepmc   +1 more source

Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes.

Molecular Endocrinology, 2013
Emily A. Witham, J. Meadows, Hanne M. Hoffmann, Shadi Shojaei, Djurdjica Coss, A. Kauffman, P. Mellon   +6 more
semanticscholar   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source