Results 241 to 250 of about 1,253,551 (390)

Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA polymerase II productive elongation. [PDF]

Cell Rep
Cornejo KG, Venegas A, Sono MH, Door M, Gutierrez-Ruiz B, Karabedian LB, Nandi SG, Hadisurya M, Tao WA, Dykhuizen EC, Saha RN.   +10 more
europepmc   +1 more source

In vivo imaging of immediate early gene expression dynamics segregates neuronal ensemble of memories of dual events. [PDF]

Mol Brain, 2021
Meenakshi P, Kumar S, Balaji J.
europepmc   +1 more source

Immediate early genes krox‐24 and krox‐20 are rapidly up‐regulated after wounding in the embryonic and adult mouse [PDF]

, 2002
Richard Grose, Brett S. Harris, Lisa Cooper, Piotr Topilko, Paul Martin   +4 more
openalex   +1 more source

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

Cell, 1991
S. Haskill, A. Beg, S. Tompkins, John S. Morris, A. Yurochko, A. Sampson‐Johannes, K. Mondal, P. Ralph, A. Baldwin   +8 more
semanticscholar   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Drosophila Ortholog of Mammalian Immediate-Early Gene Npas4 is Specifically Responsive to Reversal Learning. [PDF]

Neurosci Bull, 2021
Liu T, Wang L, Li Q.
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Investigating the role of an immediate early gene FOS as a potential regulator of autophagic response to hypoglycemia in embryonic hypothalamic neurons. [PDF]

Clin Transl Sci
Ramakrishnan RK, Srivastava A, Rajan R, Abusnana S, Mussa BM.   +4 more
europepmc   +1 more source

Fos Facilitates Gallid Alpha-Herpesvirus 1 Infection by Transcriptional Control of Host Metabolic Genes and Viral Immediate Early Gene. [PDF]

Viruses, 2021
Wang Z, Qiao Y, Chen Z, Liang Y, Cui L, Zhang Y, Li X, Xu L, Wei P, Liu S, Li H.   +10 more
europepmc   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source