Results 21 to 30 of about 1,253,551 (390)

Approaches and considerations of studying neuronal ensembles: a brief review

open access: yesFrontiers in Cellular Neuroscience, 2023
First theorized by Hebb, neuronal ensembles have provided a framework for understanding how the mammalian brain operates, especially regarding learning and memory.
Cameron J. Davidson   +4 more
doaj   +1 more source

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

open access: yes, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael   +9 more
core   +1 more source

Nicotinamide adenine dinucleotide promotes synaptic plasticity gene expression through regulation N-methyl-D-aspartate receptor/Ca2+/Erk1/2 pathway

open access: yesChinese Journal of Physiology, 2021
Nicotinamide adenine dinucleotide (NADH) has been reported to regulate synaptic plasticity recently, while its role in this process remains unclear. To explore the contribution and the underlying mechanisms of NADH regulating synaptic plasticity, here ...
Xiao-Yu Liu   +8 more
doaj   +1 more source

Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection [PDF]

open access: yes, 1984
Interstitial pneumonia linked with reactivation of latent human cytomegalovirus due to iatrogenic immunosuppression can be a serious complication of bone marrow transplantation therapy of aplastic anaemia and acute leukaemia1.
A Ebeling   +36 more
core   +1 more source

Temporal control of immediate early gene induction by light.

open access: yesPLoS ONE, 2009
BackgroundThe light-gated cation channel channelrhodopsin-2 (ChR2) is a powerful tool for the optical induction of action potentials in neurons. Mutations of the cysteine 128 (C128) residue have been shown to greatly extend the lifetime of the conducting
Philipp Schoenenberger   +2 more
doaj   +1 more source

Reward Network Immediate Early Gene Expression in Mood Disorders

open access: yesFrontiers in Behavioral Neuroscience, 2017
Over the past three decades, it has become clear that aberrant function of the network of interconnected brain regions responsible for reward processing and motivated behavior underlies a variety of mood disorders, including depression and anxiety. It is
Alfred J. Robison   +2 more
doaj   +1 more source

Age-related Changes in Lateral Entorhinal and CA3 Neuron Allocation Predict Poor Performance on Object Discrimination

open access: yesFrontiers in Systems Neuroscience, 2017
Age-related memory deficits correlate with dysfunction in the CA3 subregion of the hippocampus, which includes both hyperactivity and overly rigid activity patterns. While changes in intrinsic membrane currents and interneuron alterations are involved in
Andrew P. Maurer   +13 more
doaj   +1 more source

Time course of immediate early gene protein expression in the spinal cord following conditioning stimulation of the sciatic nerve in rats. [PDF]

open access: yesPLoS ONE, 2015
Long-term potentiation induced by conditioning electrical stimulation of afferent fibers is a widely studied form of synaptic plasticity in the brain and the spinal cord.
Ognjen Bojovic   +4 more
doaj   +1 more source

TPH2 Deficiency Influences Neuroplastic Mechanisms and Alters the Response to an Acute Stress in a Sex Specific Manner

open access: yesFrontiers in Molecular Neuroscience, 2018
Dysregulations of the central serotoninergic system have been implicated in several psychopathologies, characterized by different susceptibility between males and females.
Paola Brivio   +8 more
doaj   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

open access: yes, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J.   +4 more
core   +3 more sources

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