Results 321 to 330 of about 1,253,551 (390)

Functional genomic screens to identify and validate neuro-developmental modulators of immediate early genes, Arc and Bdnf

Vivek Kumar Sahoo
openalex   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

The effect of development on spatial pattern separation in the hippocampus as quantified by the Homer1a immediate-early gene

, 2013
Jeanne Xie
openalex   +1 more source

PKR dependent upregulation of immediate early genes and anti-inflammatory cytokine IL-10.

, 2007
Arindam Chakrabarti
openalex   +1 more source

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Amygdala kindling and immediate-early genes

Molecular Brain Research, 1995
We examined if the first afterdischarge (AD) following a kindling stimulation to the amygdala is a necessary and/or sufficient stimulus for immediate-early gene (IEG) activation and whether activity that results in IEG expression in the amygdala was sufficient to cause activation in the hippocampus.
B J, Chiasson, Z, Dennison, H A, Robertson   +2 more
openaire   +2 more sources

Calcium regulation of immediate-early response genes

Cell Calcium, 1994
A rise in intracellular Ca2+ concentration induces the transcription of a number of eukaryotic genes through transcription factors interacting with calcium response elements. Immediate-early response genes encode proteins that couple extracellular signals to phenotypic alterations by modulating the transcription rates of target genes.
E, Roche, M, Prentki
openaire   +2 more sources

Immediate early response genes and cell transformation

Pharmacology & Therapeutics, 2013
Cancer has been described as not one disease, but several, each with unique characteristics, symptoms, prognostics and outcomes. Underlying this complexity is a differential expression of genes, leading to a motley of phenotypes which orchestrate the hallmarks of cancer.
Shannon, Healy, Protiti, Khan, James R, Davie   +2 more
openaire   +2 more sources

Calcium regulation of immediate early gene transcription

Journal of Physiology-Paris, 1992
Cellular immediate early genes (IEGs) are a class of genes whose transcription is transiently activated within minutes of exposure of cells to a wide range of extracellular stimuli. In mature neurons IEG expression can be triggered by a variety of neutrotransmitters and neurotrophic factors.
M E, Greenberg, M A, Thompson, M, Sheng
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Immediate early gene transcription and synaptic modulation

Journal of Neuroscience Research, 1999
Long-term changes in gene expression appear to be critical to the formation of memory, but little is known about its stimulus- transcription coupling. Numerous studies in the last decade, by focusing on unraveling this signal transduction pathway, have investigated the potential role of the immediate-early genes in this process.
M, Walton, C, Henderson, S, Mason-Parker, P, Lawlor, W C, Abraham, D, Bilkey, M, Dragunow   +6 more
openaire   +2 more sources