Activation of frontal neocortical areas by vocal production in marmosets
Frontiers in Integrative Neuroscience, 2010 Primates often rely on vocal communication to mediate social interactions. Although much is known about the acoustic structure of primate vocalizations and the social context in which they are usually uttered, our knowledge about the neocortical control ...
Cristiano S Simões +17 more
doaj +1 more source
NPTX2 and cognitive dysfunction in Alzheimer’s Disease
eLife, 2017 Memory loss in Alzheimer’s disease (AD) is attributed to pervasive weakening and loss of synapses. Here, we present findings supporting a special role for excitatory synapses connecting pyramidal neurons of the hippocampus and cortex with fast-spiking ...
Mei-Fang Xiao +19 more
doaj +1 more source
The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]
, 1991 The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard +3 more
core +1 more source
Vocalization induced cFos expression in marmoset cortex
Frontiers in Integrative Neuroscience, 2010 All nonhuman primates communicate with conspecifics using vocalizations, a system involving both the production and perception of species-specific vocal signals.
Cory eMiller +4 more
doaj +1 more source
Mef2 induction of the immediate early gene Hr38/Nr4a is terminated by Sirt1 to promote ethanol tolerance. [PDF]
, 2018 Drug naïve animals given a single dose of ethanol show changed responses to subsequent doses, including the development of ethanol tolerance and ethanol preference. These simple forms of behavioral plasticity are due in part to changes in gene expression
Adhikari, P +3 more
core +1 more source
Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor [PDF]
, 1994 We have shown previously that the antiviral function of CD4+ T lymphocytes against murine cytomegalovirus (MCMV) is associated with the release of interferon- (IFN-).
Hengel, Hartmut +5 more
core +3 more sources
Schizophrenia: What’s Arc Got to Do with It?
Frontiers in Behavioral Neuroscience, 2017 Human studies of schizophrenia are now reporting a previously unidentified genetic convergence on postsynaptic signaling complexes such as the activity-regulated cytoskeletal-associated (Arc) gene. However, because this evidence is still very recent, the
Francesca Managò, Francesco Papaleo
doaj +1 more source
Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes. [PDF]
, 2017 The histone variant H2A.Z is an essential and conserved regulator of eukaryotic gene transcription. However, the exact role of this histone in the transcriptional process remains perplexing.
Bailey, Emma R +7 more
core +1 more source
Frontiers in Integrative Neuroscience, 2010 The neocortex plays a critical role in the gradual formation and storage of remote declarative memories. Because the circuitry mechanisms of systems-level consolidation are not well understood, the precise cortical sites for memory storage and the nature
Pavel A Gusev, Alexander N Gubin
doaj +1 more source
Genes & Development, 1988 Mature virions of herpes simplex virus type 1 contain an activating factor that primes transcription from the five virally encoded immediate early (IE) genes. This activator is specified by a 65-kD polypeptide termed VP16.
S. Triezenberg +2 more
semanticscholar +1 more source