Results 51 to 60 of about 1,253,551 (390)

Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype

open access: yesFrontiers in Neuroanatomy, 2021
The transcription factor Nurr1 is a member of the steroid hormone nuclear receptor superfamily. Ablation of Nurr1 expression arrests mesencephalic dopamine neuron differentiation while attenuation of Nurr1 in the subiculum and hippocampus impairs ...
Evangel Kummari   +4 more
doaj   +1 more source

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

open access: yesJournal of Cell Biology, 1991
Human umbilical vein endothelial (HUVE) cells have been previously reported to express the genes for the A and B chains of PDGF and to secrete PDGF-related factors into culture media.
D. Bradham   +3 more
semanticscholar   +1 more source

Calcium Influx via the NMDA Receptor Induces Immediate Early Gene Transcription by a MAP Kinase/ERK-Dependent Mechanism

open access: yesJournal of Neuroscience, 1996
The regulation of gene expression by neurotransmitters is likely to play a key role in neuroplasticity both during development and in the adult animal. Therefore, it is important to determine the mechanisms of neuronal gene regulation to understand fully
Z. Xia   +3 more
semanticscholar   +1 more source

Identification of the Immediate-Early Genes of Cyprinid Herpesvirus 2

open access: yesViruses, 2020
Cyprinid herpesvirus 2 (CyHV-2), which infects goldfish and crucian carp causing high mortality, is an emerging viral pathogen worldwide. The genome of CyHV-2 is large and comprises double-stranded DNA, including several genes similar to cyprinid ...
Ruizhe Tang   +4 more
semanticscholar   +1 more source

An acidic region of the 89K murine cytomegalovirus immediate early protein interacts with DNA [PDF]

open access: yes, 1992
The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (MCMV), interacts with core histones, which can mediate the association of pp89 with DNA.
Koszinowski, Ulrich H.   +3 more
core   +1 more source

T-cell activation and early gene response in dogs. [PDF]

open access: yesPLoS ONE, 2015
T-cells play a crucial role in canine immunoregulation and defence against invading pathogens. Proliferation is fundamental to T-cell differentiation, homeostasis and immune response.
Sally-Anne Mortlock   +2 more
doaj   +1 more source

Immediate Early Genes in Blood Pressure Regulation

open access: yesClinical and Experimental Hypertension, 1996
The immediate early genes c-fos and c-jun are transcription regulating factors. c-fos expression is widely used as a marker of neuronal activation and has been used in this study to identify those neurons, presumably vasomotor neurons, that are activated after interventions that alter blood pressure. c-fos and c-jun are expressed in the rostral ventral
Minson, Jane B   +5 more
openaire   +2 more sources

The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis

open access: yesPLoS ONE, 2013
Initiation of and progression through chondrogenesis is driven by changes in the cellular microenvironment. At the onset of chondrogenesis, resting mesenchymal stem cells are mobilized in vivo and a complex, step-wise chondrogenic differentiation program
F. Spaapen   +11 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Platelet-derived growth factor stimulates Src-dependent mRNA stabilization of specific early genes in fibroblasts. [PDF]

open access: yes, 2005
The Src family of protein-tyrosine kinases (SFKs) participates in a variety of signal transduction pathways, including promotion of cell growth, prevention of apoptosis, and regulation of cell interactions and motility.
Bromann, Paul Andrew   +5 more
core   +1 more source

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