Results 111 to 120 of about 450,843 (345)
Egr1, a member of the Egr family of transcription factors, and Arc are immediate early genes known to play major roles in synaptic plasticity and memory.
Zsuzsa ePenke +5 more
doaj +1 more source
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
Research progress on the role of immediate early genes in the pathogenesis of temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is a common chronic neurological disorder caused by highly synchronized abnormal discharges of neurons in the cerebral cortex.
ZHANG Wei, QI Shuya, TAN Guohe
doaj +1 more source
Cuttlebone‐inspired metamaterials exploit a septum‐wall architecture to achieve excellent mechanical and functional properties. This review classifies existing designs into direct biomimetic, honeycomb‐type, and strut‐type architectures, summarizes governing design principles, and presents a decoupled design framework for interpreting multiphysical ...
Xinwei Li, Zhendong Li
wiley +1 more source
Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 [PDF]
INTRODUCTION: Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
Bell, A.K. +9 more
core
Regulation of Human Cytomegalovirus Immediate-Early Gene Expression
The positive and negative cis-acting elements that affect transcription from the human cytomegalovirus major immediate-early (MIE) promoter and the viral and cellular proteins that bind to these elements are discussed. The data obtained using in vitro transcription and transient transfection assays are reviewed and compared to recent data using ...
J L, Meier, M F, Stinski
openaire +2 more sources
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel +13 more
wiley +1 more source
This study presents the first human neural organoid culture model capable of rapidly exhibiting long‐distance neural network propagation, thus delivering a system to experimentally investigate large‐scale communication during normal and diseased states.
Megh Dipak Patel +6 more
wiley +1 more source
The Epstein-Barr Virus Immediate-Early Gene Product, BRLF1, Interacts with the Retinoblastoma Protein during the Viral Lytic Cycle [PDF]
Valerie Zacny +2 more
openalex +1 more source

