Engineering combinatorial and dynamic decoders using synthetic immediate-early genes [PDF]
, 2019 Pavithran T. Ravindran +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
Complement C4-deficient mice have a high mortality rate during PTZ-induced epileptic seizures, which correlates with cognitive problems and the deficiency in the expression of Egr1 and other immediate early genes. [PDF]
Front Cell Neurosci, 2023 Veremeyko T +3 more
europepmc +1 more source
Increased expression of immediate early response gene 3 protein promotes aggressive progression and predicts poor prognosis in human bladder cancer [PDF]
, 2018 Jian‐Heng Ye +12 more
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Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Role of the host cell in bacteriophage T4 development. II. Characterization of host mutants that have pleiotropic effects on T4 growth [PDF]
, 1980 Mutant host-defective Escherichi coli that fail to propagate bacteriophage T4 and have a pleiotropic effect on T4 development have been isolated and characterized.
Lielausis, Ilga +3 more
core
Advanced Materials, Volume 37, Issue 13, April 2, 2025.A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou +10 more
wiley +1 more source
Cloning of mid-G_1 serum response genes and identification of a subset regulated by conditional myc expression [PDF]
, 1994 The emergence of cells from a quiescent G_0 arrested state into the cell cycle is a multistep process that begins with the immediate early response to mitogens and extends into a specialized G_1 phase.
Tavtigian, Sean V. +2 more
core
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
Advanced Materials, EarlyView.This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang +13 more
wiley +1 more source