Results 11 to 20 of about 450,843 (345)

MECHANISMS OF IMMEDIATE-EARLY GENES ACTIVATION

Медицинский вестник Юга России, 2016
In our article, we focus on molecular mechanisms of immediately early genes expression. We discuss extracellular signals that are transduced into the nucleus through a variety of signaling mechanisms to elicit changes in patterns of immediately early ...
P. P. Polyakov, A. S. Lipatova, A. H. Kade   +2 more
doaj   +3 more sources

Distress Regulates Different Pathways in the Brain of Common Carp: A Preliminary Study

Animals, 2021
In this study, a stress trial was conducted with common carp, one of the most important species in aquaculture worldwide, to identify relevant gene regulation pathways in different areas of the brain.
Alexander Burren, Constanze Pietsch
doaj   +1 more source

Cell arrest and cell death in mammalian preimplantation development [PDF]

, 2011
The causes, modes, biological role and prospective significance of cell death in preimplantation development in humans and other mammals are still poorly understood.
A Bettegowda, A Bettegowda, A Bettegowda, A Jurisicova, AE Crosier, AS Jakobsen, C Robert, C Wrenzycki, D Fabian, DH Betts, E Memili, E Vanneste, Eckhard Wolf, Felix A. Habermann, FF Paula-Lopes, FJ Pomar, Fred Sinowatz, G Kroemer, GE Exley, GS Salvesen, H Badr, HM Knijn, Horst-Dieter Reichenbach, I Robertson, J Fujita, J Laurincik, J Wang, J Yuan, JE Dietrich, JO Gjorret, JO Gjorret, Joerg Gromoll, K Goossens, K Hardy, L Dubrez-Daloz, L Galluzzi, L Leibfried, L Vandaele, LA Pradelli, M Boelhauve, M Lamkanfi, Marc Boelhauve, ME Guicciardi, MG Diskin, Myriam Reichenbach, P Chomczynski, P Lonergan, PS Malhi, R Draker, R Sartori, S Bilodeau-Goeseels, S Cory, SA Bustin, Sandra Leidenfrost, TA Brevini, TJ Fan, Tuna Güngör, Y Gavrieli   +57 more
core   +13 more sources

Prions induce an early Arc response and a subsequent reduction in mGluR5 in the hippocampus

Neurobiology of Disease, 2022
Synapse dysfunction and loss are central features of neurodegenerative diseases, caused in part by the accumulation of protein oligomers. Amyloid-β, tau, prion, and α-synuclein oligomers bind to the cellular prion protein (PrPC), resulting in the ...
Daniel Ojeda-Juárez, Jessica A. Lawrence, Katrin Soldau, Donald P. Pizzo, Emily Wheeler, Patricia Aguilar-Calvo, Helen Khuu, Joy Chen, Adela Malik, Gail Funk, Percival Nam, Henry Sanchez, Michael D. Geschwind, Chengbiao Wu, Gene W. Yeo, Xu Chen, Gentry N. Patrick, Christina J. Sigurdson   +17 more
doaj   +1 more source

Temporal pattern of Fos and Jun families expression after mitogenic stimulation with FGF-2 in rat neural stem cells and fibroblasts

Brazilian Journal of Medical and Biological Research, 2023
Intense stimulation of most living cells triggers the activation of immediate early genes, such as Fos and Jun families. These genes are important in cellular and biochemical processes, such as mitosis and cell death.
A.C. Mosini, P.C. Mazzonetto, M.L. Calió, C. Pompeu, F.H. Massinhani, T.K.E. Nakamura, J.M. Pires, C.S. Silva, M.A. Porcionatto, L.E. Mello   +9 more
doaj   +1 more source

The Immediate Early Response of Lens Epithelial Cells to Lens Injury

Cells, 2022
Cataracts are treated by lens fiber cell removal followed by intraocular lens (IOL) implantation into the lens capsule. While effective, this procedure leaves behind numerous lens epithelial cells (LECs) which undergo a wound healing response that ...
Samuel G. Novo, Adam P. Faranda, Mahbubul H. Shihan, Yan Wang, Ananya Garg, Melinda K. Duncan   +5 more
doaj   +1 more source

Call‐specific patterns of neural activation in auditory processing of Richardson’s ground squirrel alarm calls

Brain and Behavior, 2020
Introduction Richardson's ground squirrels use alarm calls to warn conspecifics about potential predatory threats. Chirp calls typically indicate high levels of threat from airborne predators, while whistle calls are associated with lower levels of ...
Angela R. Freeman, James F. Hare, Heather K. Caldwell   +2 more
doaj   +1 more source

Embryonic stem cells become mechanoresponsive upon exit from ground state of pluripotency [PDF]

Open Biology, 2019
Stem cell fate decisions are driven by a broad array of signals, both chemical and mechanical. Although much progress has been made in our understanding of the impact of chemical signals on cell fate choice, much less is known about the role and ...
C. M. Verstreken, C. Labouesse, C. C. Agley, K. J. Chalut   +3 more
doaj   +1 more source

Genome-wide gene expression analysis of anguillid herpesvirus 1 [PDF]

, 2013
<p>Background: Whereas temporal gene expression in mammalian herpesviruses has been studied extensively, little is known about gene expression in fish herpesviruses.
Davison, A.J., Engelsma, M.Y., Peeters, B.P.H., Rottier, P.J.M., van Beurden, S.J.   +4 more
core   +3 more sources

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael, Calendar, R., Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Gold, L., Jahn, Gerhard, Rüger, Rüdiger, Schaffner, Walter, Stoerker, Jay, Weber, Frank   +9 more
core   +1 more source