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The effect of development on spatial pattern separation in the hippocampus as quantified by the Homer1a immediate-early gene

, 2013
Jeanne Xie
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Amygdala kindling and immediate-early genes

Molecular Brain Research, 1995
We examined if the first afterdischarge (AD) following a kindling stimulation to the amygdala is a necessary and/or sufficient stimulus for immediate-early gene (IEG) activation and whether activity that results in IEG expression in the amygdala was sufficient to cause activation in the hippocampus.
B J, Chiasson, Z, Dennison, H A, Robertson   +2 more
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Calcium regulation of immediate-early response genes

Cell Calcium, 1994
A rise in intracellular Ca2+ concentration induces the transcription of a number of eukaryotic genes through transcription factors interacting with calcium response elements. Immediate-early response genes encode proteins that couple extracellular signals to phenotypic alterations by modulating the transcription rates of target genes.
E, Roche, M, Prentki
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Immediate early response genes and cell transformation

Pharmacology & Therapeutics, 2013
Cancer has been described as not one disease, but several, each with unique characteristics, symptoms, prognostics and outcomes. Underlying this complexity is a differential expression of genes, leading to a motley of phenotypes which orchestrate the hallmarks of cancer.
Shannon, Healy, Protiti, Khan, James R, Davie   +2 more
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Calcium regulation of immediate early gene transcription

Journal of Physiology-Paris, 1992
Cellular immediate early genes (IEGs) are a class of genes whose transcription is transiently activated within minutes of exposure of cells to a wide range of extracellular stimuli. In mature neurons IEG expression can be triggered by a variety of neutrotransmitters and neurotrophic factors.
M E, Greenberg, M A, Thompson, M, Sheng
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Immediate early gene transcription and synaptic modulation

Journal of Neuroscience Research, 1999
Long-term changes in gene expression appear to be critical to the formation of memory, but little is known about its stimulus- transcription coupling. Numerous studies in the last decade, by focusing on unraveling this signal transduction pathway, have investigated the potential role of the immediate-early genes in this process.
M, Walton, C, Henderson, S, Mason-Parker, P, Lawlor, W C, Abraham, D, Bilkey, M, Dragunow   +6 more
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Light, immediate-early genes, and circadian rhythms

Behavior Genetics, 1996
Many diverse behaviors exhibit clear circadian rhythms in their expression. In mammals, these rhythms originate from a neural circadian clock located in the suprachiasmatic nuclei (SCN). Recently, signaling pathways activated by light in the SCN have begun to be identified.
J M, Kornhauser, K E, Mayo, J S, Takahashi   +2 more
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Immediate early gene expression during morphine withdrawal

Neuropharmacology, 1995
The expression of immediate early genes (IEG)s c-fos, c-jun and zif/268 was studied during naloxone-precipitated morphine withdrawal in various organs of the rat. Dependence was induced over a period of 6 days by a graded regimen of 6-hourly injections.
Beckmann A.M., Matsumoto I., Wilce P.A.
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Immediate early genes

2002
Abstract The term immediate early gene (IEG) was borrowed from virology. During the infectious cycle, the viral proteins are expressed in an orderly programme, which involves immediate early, delayed early, and late proteins (Honess and Roizman 1974; Weinheimer and McKnight 1987).
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