Results 11 to 20 of about 94,038 (306)
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu +3 more
doaj +1 more source
Converter Phenotype: A New Profile That Is Not Exclusive to Taxanes
Introduction: Phenotype I hypersensitivity reactions are the most commonly reported drug reactions; however, precision medicine has made it possible to characterize new phenotypes. A recent communication proposed the existence of a “converter phenotype,”
Teodorikez Wilfox Jimenez-Rodriguez +13 more
doaj +1 more source
Protein contact dermatitis - case report [PDF]
Protein contact dermatitis is a skin condition not well known and underdiagnosed by dermatologists, resulting from an IgE-mediated allergic reaction. Clinically it presents as a chronic hand and/or forearms eczema of occupational origin, especially in ...
Ana Rita Rodrigues Barata +1 more
doaj +1 more source
Immediate hypersensitivity to chlorhexidine [PDF]
AbstractChlorhexidine is a widely used and effective antiseptic agent. Although skin contact is usually well tolerated, it may cause both immediate and delayed hypersensitivity reactions. We report a case of immediate hypersensitivity to chlorhexidine causing both skin and respiratory symptoms following occupational exposure to chlorhexidine in a ...
Mi Vu +4 more
openaire +3 more sources
Contrast Medium Hypersensitivity: A Large Italian Study with Long-Term Follow-Up
Hypersensitivity reactions (HRs) to contrast media (CM) are a major problem. We compared differences of HRs to iodinated contrast media (ICM) versus gadolinium-based contrast media (GBCM), collecting data on prevalence, type, latency and severity ...
Eleonora Nucera +7 more
doaj +1 more source
Skin testing in patients with hypersensitivity reactions to iodinated contrast media - a European multicenter study [PDF]
BACKGROUND: Iodinated contrast media cause both immediate and nonimmediate hypersensitivity reactions. The aim of this prospective study was to determine the specificity and sensitivity of skin tests in patients who have experienced such reactions ...
Aberer, W +15 more
core +2 more sources
Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer +3 more
doaj +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard +3 more
core +1 more source
siRNA knockdown of SPHK1 in vivo protects mice from systemic, type-I Allergy. [PDF]
Systemic anaphylaxis is considered to be a typical immediate hypersensitivity response, determined by the activation of immune cells, via antigen-induced aggregation of IgE-sensitized FcεRI cells.
Alirio Jose A. J. Melendez +2 more
core +2 more sources
Contact urticaria to giraffe hair [PDF]
Background: Immediate-type hypersensitivity to animal proteins is a common problem in people occupationally exposed to animals. Methods: A 19-year-old female working as a voluntary zookeeper in her off-time suffered from hives on her forearms following ...
Herzinger, T. +3 more
core +1 more source

