Results 71 to 80 of about 133,536 (298)

Stabilizing Removable Partial Dentures by Immediate or Delayed Loading of Mini-implants: Chewing Efficiency in a Randomized Controlled Clinical Trial.

, 2020
PURPOSE The aim of this investigation was to compare the chewing efficiency after immediate and delayed loading of mini-implants that served as supplementary support for removable partial dentures (RPDs).
Schimmel, Martin, Lucas, Christian, Mundt, Torsten, Schwahn, Christian, Heinemann, Friedhelm, Al Jaghsi, Ahmad   +5 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Immediate vs. delayed endosseous integration of maxi implants: a torque removal animal study [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects, 2017
Background. Delayed loading is one of the concerns in implant patients. Immediate loading can solve the problem and make patients more satisfied. The present study aimed to compare the removal torque of maxi implants under different loading ...
Hanif Allahbakhshi, Fariborz Vafaee, Mehrdad Lotfazar, Ahmad Hasan Ahangary, Masoumeh Khoshhal, Farnoush Fotovat   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Associação de enxertos ósseo e conjuntivo à carga imediata na região anterior [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Curso de OdontologiaO presente trabalho tem como objetivo abordar o tema carga imediata em implantes unitários.
Tames, Rodrigo Speggiorin
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Immediate loading: a new implant technique with immediate loading and aesthetics: Nobel Active™.

ORAL & implantology, 2008
The aim of this study is to evaluate the short time aesthetic and functional outcome of a new implant system, the Nobel Active™. The Nobel Active™ features several innovations such as an extensive self-drilling capacity, axial and radial bone compression and an inward tapered collar allowing for marginal bone maintance an soft tissue stabilization ...
Moretto, D, GARGARI, MARCO, Nordsjo, E, Gloria, F, OTTRIA, LILIANA   +4 more
openaire   +2 more sources

Immediate Loading of Dental Implants with Fixed Prosthodontic Constructions Advantages and Methods

, 2022
“Immediate loading of implants” implies loading of implants after extraction of a tooth. The goal of our study was to observe the loss of keratinized gums and bone tissue in the region surrounding the alveolar ridge after tooth extraction, and to compare
Dolidze, Tamar, Kublashvili, Marika
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source