Immobilization Stress and Direct Glucocorticoid Effects on Rat Septohippocampus
International Journal of Neuroscience, 1988The rat septohippocampal cholinergic system to a large extent regulates the adaptive physiological and behavioral response to stress. The mesoseptal dopaminergic (DA) system, one of the converging inputs to the lateral septum, exerts a tonic inhibitory action on the septohippocampal cholinergic neurons.
Y, Finkelstein +4 more
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Effects of immobilization stress on shock discrimination performance in rats
Physiology & Behavior, 1982It has been suggested that acute stress induces analgesia in rats and mice. However, stress can have a myriad of debilitating effects on organisms, and it is not clear whether stress decreases the perceived intensity of the painful stimulus (i.e., a change in sensitivity) or decreases the willingness or ability of the organism to carry out the ...
D M, Grilly, J P, Dugovics
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Mechanism of oxidative stress in skeletal muscle atrophied by immobilization
American Journal of Physiology-Endocrinology and Metabolism, 1993To clarify the mechanism of oxidative stress in skeletal muscle atrophied by immobilization, we measured the activities of antioxidant enzymes and xanthine oxidase (XOD) and carried out the cytochemical study of hydrogen peroxide in a typical slow red muscle, the soleus.
H, Kondo +4 more
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Immobilization Stress Induces BDNF in Rat Submandibular Glands
Journal of Dental Research, 2006Brain-derived neurotrophic factor (BDNF) promotes survival and differentiation of the cells of the central and peripheral nervous systems. BDNF has been identified in non-neural tissue, including the heart, lung, platelets, lymphocytes, and lacrimal glands. Immobilization stress modifies BDNF mRNA expression in some organs.
K, Tsukinoki +7 more
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Stress of Immobilization: Description and Validation of a Restraining Technique for Rats
Psychological Reports, 1981Various techniques have been developed over the past several years to study the effects of the stress of immobilization on the rat. The technique proposed in this paper provides effective restraint. It has the added advantage that potentially contaminating effects of uncontrolled secondary stressors are limited. The technique was tested in five groups
R, Darlington, J, Bergeron, F, Leporé
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Analgesia produced by immobilization stress and an enkephalinase inhibitor in amphibians
Pharmacology Biochemistry and Behavior, 1995The role of endogenous opioids in modulating pain transmission in amphibians was examined by two methods known to activate endogenous opioids in mammals. Analgesia was assessed using the acetic acid test in the Northern grass frog, Rana pipiens. One or 2 h of immobilization produced a significant analgesia lasting for at least 90 min. Systemic, but not
C W, Stevens, S, Sangha, B G, Ogg
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Involvement of dynorphin in immobilization stress-induced antinociception in the mouse
European Neuropsychopharmacology, 2000The effect of antiserum against [Met(5)]-enkephalin, [Leu(5)]-enkephalin, beta-endorphin, or dynorphin A-(1-13) administered intracerebroventricularly (i.c.v.) or intrathecally (i. t.) on immobilization-induced antinociception was studied in ICR mice. Antinociception was assessed by the tail-flick assay. Immobilization of the mouse increased inhibition
H W, Suh, D K, Song, S O, Huh, Y H, Kim
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Immobilization stress-induced anorexia is mediated independent of MyD88
NeuroReport, 2016MyD88 is an adaptor protein for the toll-like receptor, which is involved in regulating innate immune function. Lipopolysaccharide-induced activation of toll-like receptor 4 signaling induces hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation and anorexia through MyD88.
Toru, Hosoi +3 more
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[Anti-stress effect of dalargin in immobilization stress in rats].
Biulleten' eksperimental'noi biologii i meditsiny, 1991The function of the isolated perfused rat hearts was studied in four groups of experiments. Group 1--included the hearts of intact animals ("absolute control"), group 2--the hearts of rats subjected to 24 hour immobilization in supine position against the background of triple intramuscular injections of placebo (control), group 3 included the hearts of
G F, Dvortsin, V N, Shatalov
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Effects of immobilization stress on the pathogenesis of acute murine toxoplasmosis
Brain, Behavior, and Immunity, 1990Stress modulates a variety of immune responses. We investigated the effects of immobilization stress on the pathogenesis of acute murine toxoplasmosis, an infection in which cell-mediated immunity is of major importance in host defense. Repetitive overnight immobilization beginning 3 days prior to infection enhanced (p less than 0.05) the mortality of ...
C C, Chao +4 more
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