Results 201 to 210 of about 2,310,619 (425)

Faster Surface Ligation Reactions Improve Immobilized Enzyme Structure and Activity. [PDF]

open access: yesJ Am Chem Soc, 2021
Chaparro Sosa AF   +4 more
europepmc   +1 more source

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

open access: yesAdvanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro   +5 more
wiley   +1 more source

SIMPLE ENTRAPMENT OF ALCALASE IN DIFFERENT SILICA XEROGELS USING THE TWO STEPS SOL-GEL METHOD [PDF]

open access: yes, 2011
The present study has focused on the entrapment of Alcalase in different xerogels obtained by using various molar ratios of methyltriethoxysilane, dimethyldietoxisilane and tetraethoxysilane.
Chiriac, A.   +2 more
core  

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

UniZyme: A Unified Protein Cleavage Site Predictor Enhanced with Enzyme Active-Site Knowledge [PDF]

open access: yesarXiv
Enzyme-catalyzed protein cleavage is essential for many biological functions. Accurate prediction of cleavage sites can facilitate various applications such as drug development, enzyme design, and a deeper understanding of biological mechanisms. However, most existing models are restricted to an individual enzyme, which neglects shared knowledge of ...
arxiv  

Effective and Practical Stereoselective Synthesis of Nutlins Precursors by Immobilization of Privileged Chiral Mono‐Amidine Catalyst

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract A strategy for the immobilization of Johnston's Mono(AMidine) catalyst (MAM) onto polystyrene, silica and hybrid silica‐polystyrene nanoparticles is presented. The catalyst activity was evaluated in the stereoselective aza‐Henry reaction leading to the pivotal β‐amino nitroalkane precursors of the anti‐cancer agents Nutlins (with Nutlin‐3a as ...
Sofia Toldo   +8 more
wiley   +1 more source

Covalent immobilization of horseradish peroxidase onto magnetic nanoparticles [PDF]

open access: yes, 2010
The biocatalyst horseradish peroxidase (HRP) was successfully immobilized onto magnetic nanoparticles by the glutaraldehyde method. The influence of pH medium, ionic strength, the initial protein concentration, temperature and the effect of the ...
Campayo Sumalla, Tania
core  

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