Results 201 to 210 of about 112,493 (288)

Blistering barnacles: Space physiology in The Adventures of Tintin

Experimental Physiology, EarlyView.
Jacob P. Hartmann, Mathis B. Mottelson, Rasmus H. Dahl, Ronni R. Plovsing, Ronan M. G. Berg   +4 more
wiley   +1 more source

Impact of Evolving Evidence on Pharmacological Therapy for Alcohol‐Associated Hepatitis in Alberta: A Population‐Based Study of Practice Trends and MELD‐Stratified Effectiveness of Corticosteroids

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1246-1255, May 2026.
In this population‐based study in Alberta, Canada, evidence from RCTs led to a rapid reversal in pentoxifylline use, prior to formal guideline updates. Real‐world data support a modest short‐term benefit of CS and illustrate the potential of target trial emulation to assess treatment effectiveness in specific groups of patients. ABSTRACT Background and
Abdel‐Aziz Shaheen, Meng Wang, Bryce Tkachuk, Juan G. Abraldes   +3 more
wiley   +1 more source

Artificial intelligence: The great divide. [PDF]

Indian J Ophthalmol
Chaudhuri Z.
europepmc   +1 more source

Cytoreductive nephrectomy in the era of immune‐checkpoint inhibitors: back to the future?

BJU International, Volume 137, Issue 5, Page 763-769, May 2026.
Objective To investigate the role of cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC) treated with immune‐checkpoint inhibitors (ICIs). Methods A narrative review was carried out using PubMed and searching for English articles published from January 2015 to May 2025.
Rocco Simone Flammia, Riccardo Campi, Eugenio Bologna, Riccardo Bertolo, Costantino Leonardo, Fabio Calabrò, Daniele Amparore, Giuseppe Simone, on behalf of the Young Academic Urologists (YAU) Renal Cancer Working Group   +8 more
wiley   +1 more source

Immortal Time Bias in Cohort Studies: A Concept Simply Explained. [PDF]

Indian J Psychol Med
Andrade C.
europepmc   +1 more source

Impact of early and tight HbA1c control on the risk of long‐term complications and cardiovascular death in patients with type 2 diabetes from the Swedish National Diabetes Register

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3997-4009, May 2026.
Abstract Aims To assess the relationship between haemoglobin A1c (HbA1c) levels and incidence of long‐term complications in patients with type 2 diabetes (T2D). Materials and Methods This long‐term, retrospective study acquired patient data from the Swedish National Diabetes Registry and linked national registers between 1 January 1998 and 31 December ...
Julie Mount, Kristina Boye, Jeremie Lebrec, Emily Wilkes, Kari Ranta, Anders Toll, Erik Joas, Irina Sveide, Björn Eliasson, Josefine Redig   +9 more
wiley   +1 more source

Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence. [PDF]

Genes Dev
Bloom SI, Karlseder J.
europepmc   +1 more source

Evaluating the Impact of Putative Metformin Targets on Cancer Outcomes: A Drug‐Target Mendelian Randomization Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4091-4099, May 2026.
ABSTRACT Aims Observational studies show metformin use associated with lower cancer risk, although experimental evidence is inconsistent. To provide genetic validation for repositioning of metformin in cancer prevention, we assessed genetically proxied effects of putative metformin targets on cancer outcomes using a drug‐target Mendelian randomization (
Xingyu Shen, Shan Luo, Jie Zheng, Celine Sze Ling Chui, Ian Chi Kei Wong, Eric Yuk Fai Wan, Catherine Mary Schooling, Shiu Lun Au Yeung   +7 more
wiley   +1 more source

Original Sin and Education [PDF]

, 1950
Vollert, Cyril
core   +1 more source

Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells

Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu, Song Hee Lee, Ji Hyeon Kim, Seung Jin Kim, Hee Eun Kang   +4 more
wiley   +1 more source