Results 201 to 210 of about 11,576 (268)
Colorectal cancer as a complex adaptive system: integrating the hallmarks of cancer with complexity theory. [PDF]
Basbus LR.
europepmc +1 more source
Cumulative Antigen Suppression Reduces Clonal Plasma Cell Evolution in Gaucher Disease
ABSTRACT Chronic antigenic stimulation is implicated in the pathogenesis of monoclonal gammopathy and multiple myeloma, yet longitudinal human evidence linking sustained antigen exposure to modifiable clonal plasma cell evolution remains limited. Gaucher disease (GD), caused by biallelic GBA1 pathogenic variants, is characterized by accumulation of ...
Noor Ul Ain +10 more
wiley +1 more source
Artificial intelligence: The great divide. [PDF]
Chaudhuri Z.
europepmc +1 more source
ABSTRACT Minimal residual disease (MRD) is the standard for deep response assessment in multiple myeloma but requires bone marrow sampling. Whether early serum free light chain (sFLC) response provides independent prognostic information in real‐world, predominantly non‐transplant patients remains unclear.
Yubiao Pan +5 more
wiley +1 more source
ABSTRACT Introduction Continuity of care, a critical component of high‐quality primary care, was interrupted in people with diabetes mellitus during the COVID‐19 pandemic in Hong Kong. Research on whether reduced continuity of care was associated with higher complications and mortality risks is lacking.
Yuk Kam Yau +11 more
wiley +1 more source
The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible. [PDF]
Stevers NO +15 more
europepmc +1 more source
ABSTRACT Aim Sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are known to reduce serum urate levels, yet their specific impact on gout incidence in the Korean population remains underexplored. We investigated the association between SGLT2i use and incident gout using real‐world data and Mendelian randomisation (MR) analysis. Materials and Methods We
Hong Sang Choi +7 more
wiley +1 more source
Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence. [PDF]
Bloom SI, Karlseder J.
europepmc +1 more source
ABSTRACT Aim and Objective To explore how receiving gerontological nurse telephone support assisted caregivers of older adults to provide care after hospital discharge. Background Informal caregivers are vital to the recovery of older patients after hospital discharge, but often feel under‐prepared and unsupported.
Cheng Yen Loo +7 more
wiley +1 more source
Radiogenomic landscape of the hallmarks of cancer. [PDF]
Zhang G +11 more
europepmc +1 more source

