Results 231 to 240 of about 21,252 (310)

Out There No One Has a Right to Die

open access: yesBioethics, Volume 40, Issue 6, Page 565-572, July 2026.
ABSTRACT The eventual goal of space exploration is to colonize exoplanets and their moons outside our solar system. This is a dangerous and immoral endeavour. The extraterrestrial life forms encountered would be hostile, vulnerable or both, and the descendants of the original pioneers would be involuntarily exposed to hazardous conditions and ...
Matti Häyry
wiley   +1 more source

Benzbromarone as a Novel Candidate for Preventing Alzheimer's Disease: Evidence From Real‐World Data Screening and in Vitro Validation

open access: yesClinical and Translational Science, Volume 19, Issue 7, July 2026.
Drug repositioning analysis identifies candidate therapeutic agents for Alzheimer’s diseaseand supports further mechanistic and translational investigation. ABSTRACT Drug development for Alzheimer's disease (AD) remains challenging, with only a 0.4% success rate from Phase I trials to regulatory approval.
Sho Sakagami   +11 more
wiley   +1 more source

A structural bioinformatics framework for prioritizing pH-sensitive proteins from 3D structural features. [PDF]

open access: yesBMC Bioinformatics
Arsanjani AA   +6 more
europepmc   +1 more source

Differential Impact of Metabolic Bariatric Surgery Versus Semaglutide on Adverse Hepatic and Extrahepatic Outcomes in Individuals With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5684-5695, July 2026.
ABSTRACT Aim We compared the impact of metabolic bariatric surgery (MBS) versus semaglutide on clinical outcomes in individuals with metabolic dysfunction‐associated steatotic liver disease (MASLD) and type 2 diabetes (T2D). Methods Patients with MASLD and T2D who had MBS or semaglutide in 2018–2023 were identified (TriNetX database).
Weronika Stupalkowska   +5 more
wiley   +1 more source

GLP‐1 Receptor Agonist Therapy and Cardiorenal Outcomes in Type 1 Diabetes: A Propensity‐Matched Real‐World Analysis

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 6347-6357, July 2026.
ABSTRACT Aims Evidence on cardiovascular/renal outcomes associated with GLP‐1‐based therapies in type 1 diabetes (T1D) is limited. We examined the effects of GLP‐1‐based therapy on major clinical outcomes and safety, including diabetic ketoacidosis (DKA) and hypoglycemia risk, in adults with T1D in a large real‐world cohort.
Anastasios Tentolouris   +7 more
wiley   +1 more source

Effects of Unemployment benefit sanctions among young adults with and without labour market disadvantages: A register‐based target trial emulation in Finland

open access: yesInternational Journal of Social Welfare, Volume 35, Issue 3, July 2026.
Abstract To encourage transitions into employment or education, governments impose benefit sanctions on unemployed individuals who fail to comply with conditionality requirements. However, evidence on the effectiveness of such sanctions remains limited, particularly among young adults.
Jaakko Harkko   +3 more
wiley   +1 more source

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