Results 51 to 60 of about 2,500,076 (170)

Phase I dose escalation study of IO-108, an anti-LILRB2 antibody, in patients with advanced solid tumors

Journal for ImmunoTherapy of Cancer
Purpose In this first-in-human dose escalation study, the safety and efficacy of IO-108, a fully human monoclonal antibody targeting leukocyte immunoglobulin-like receptor B2 (LILRB2), was investigated in patients with advanced solid tumors as ...
Ying Zhu, Tao Huang, John Powderly, Aung Naing, Manish R Patel, Matthew H Taylor, Rong Deng, Kyu Hong, Luke Chung, Hongyu Tian, Wen Hong Lin, Paul Woodard, Nathan Siemers, Hong Xiang, Donna Valencia, X Charlene Liao, Xiao Min Schebye   +16 more
doaj   +1 more source

S276: POVETACICEPT (ALPN-303), A POTENT DUAL BAFF/APRIL ANTAGONIST, FOR THE TREATMENT OF AUTOIMMUNE CYTOPENIAS AND OTHER ANTIBODY-RELATED DISEASES

HemaSphere, 2023
Stacey Dillon, Rupert Davies, Jason Lickliter, Kristi Mclendon, Kristi Kristi L. Manjarrez, Bs, Alina Smith, Krystalyn Hudson, Lori Blanchfield, Russel Sanderson, Allison Chunyk, Tiffany Blair, Amanda Enstrom, Hany Zayed, Stanford Peng   +13 more
doaj   +1 more source

Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems-wide analysis of immune cell, cytokine, and symptom measures

Military Medical Research
Background One-third of veterans returning from the 1990–1991 Gulf War reported a myriad of symptoms including cognitive dysfunction, skin rashes, musculoskeletal discomfort, and fatigue. This symptom cluster is now referred to as Gulf War Illness (GWI).
Esha Sultana, Nandan Shastry, Rishabh Kasarla, Jacob Hardy, Fanny Collado, Kristina Aenlle, Maria Abreu, Emily Sisson, Kimberly Sullivan, Nancy Klimas, Travis J. A. Craddock   +10 more
doaj   +1 more source

Immunogenicity and efficacy of an mRNA vaccine expressing a virus-like particle spike antigen against SARS-CoV-2

npj Vaccines
The COVID-19 pandemic spurred mRNA vaccine innovation, but new SARS-CoV-2 variants highlight the need for vaccines with improved potency and durability.
Jason P. Laliberte, Yingyun Cai, Tara Kenny, Yi Zhang, Kuishu Ren, Kim Rosenthal, Daniel Flores, Richard Roque, Oliver Acton, Vanessa Cadevilla Peano, Noel Janney, Vinita Puri, Sarah Siddiqui, Angela Pack, Giune Padilla, Seme Diallo, Hibret Adissu, Rakesh Choudhary, Hawley Pruitt, Yi-Han Cheng, George Thom, Michael Newton, Cheyne Kurokawa, Johnathan Guest, Phillip Swanson, Yueh-Ming Loo, Joseph R. Francica, Wade Blair, Mark Esser   +28 more
doaj   +1 more source

Study on nutritional status and incidence of sarcopenia in elderly patients with chronic heart failure. [PDF]

Asia Pac J Clin Nutr
Song S, Du H, Lu X, Luo B, Li Z.
europepmc   +1 more source

P1257: SMART101 DONOR T-LYMPHOID PROGENITORS TO ACCELERATE IMMUNE RECONSTITUTION POST-HAPLOIDENTICAL PERIPHERAL BLOOD STEM CELL TRANSPLANTATION WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE: SI101-02 PHASE I/II

HemaSphere, 2023
Fabio Ciceri, Régis Peffault de Latour, Raynier Devillier, Patrizia Chiusolo, Aurelie Bauquet, Laura Simons, Pierre Heimendinger, Pierre Gaudeaux, Olivier Negre, Tayebeh-Shabi Soheili, Juliette Paillet, Isabelle Andre, Sebastien Oster, Marina Cavazzana, Frederic Lehmann   +14 more
doaj   +1 more source

Anoikis-Related Genes Signature Contributes to Predicting Prognosis and Response to Immunotherapy in Lung Squamous Cell Carcinoma. [PDF]

Med Sci Monit
Lu H, Huang W, Shen Q, Liu R.
europepmc   +1 more source

A hybrid PKPD agent-based model of the tumour immune interaction: effects of anti-cancer combination therapy. [PDF]

J Pharmacokinet Pharmacodyn
Truong VT, Lythe G, Vicini P, Yates JWT, Dubois VFS.   +4 more
europepmc   +1 more source

Review of the Effects of Anesthetic Techniques and Medications on the Immune Response During the Perioperative Period. [PDF]

Med Sci Monit
Radkowski P, Pisula MJ, Malicki DK, Szewczyk M, Marczuk K, Mamala M, Grabarczyk Ł.   +6 more
europepmc   +1 more source

Baseline Tumor Features and Systemic Immune Dynamics Underlying Efficacy in MSS Metastatic Colorectal Cancer Treated with Regorafenib, Ipilimumab, and Nivolumab. [PDF]

Cancer Immunol Res
Ye J, Wang C, Egelston CA, Guo W, Mannan R, Lee PP, Fakih MG.   +6 more
europepmc   +1 more source