Results 61 to 70 of about 5,479,910 (356)

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

open access: yes, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda   +7 more
core   +1 more source

Sleep and Immunity [PDF]

open access: yesNeuroscience and Behavioral Physiology, 2020
This review presents data on changes in measures of innate and adaptive immunity associated with the state of sleep. The effects of restricted and prolonged sleep duration on measures of morbidity, mortality, and susceptibility to infectious diseases and the effects of vaccination are discussed.
openaire   +3 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles   +4 more
wiley   +1 more source

Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction

open access: yesOncoImmunology, 2018
Chemokines are essential mediators of cellular trafficking, interactions and tumor development. Though adoptive cell therapy (ACT) has been a tremendous success in the treatment of metastatic melanoma (MM), a major obstacle for successful ACT, is limited
Manja Idorn   +8 more
doaj   +1 more source

Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials

open access: yesNature Communications, 2023
Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV) fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before their first RSV ...
Bahar Ahani   +20 more
doaj   +1 more source

Immune Logics ain't that Immune

open access: yesLogic and Logical Philosophy, 2022
Da Ré and Szmuc argue that while there is a symmetry between ‘infectious’ and ‘immune’ logics, this symmetry fails w.r.t. extending an algebra with an immune or an infectious element. In this paper, I show that the symmetry also fails w.r.t. defining a new logical operation from a given set of primitive (Boolean) operations.
openaire   +2 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Training the Fetal Immune System Through Maternal Inflammation-A Layered Hygiene Hypothesis. [PDF]

open access: yes, 2020
Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune
Apostol, April C   +2 more
core  

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Age and Gender Difference in the Association of Metabolic Syndrome and Peripheral Artery Disease Among Patients With Type 2 Diabetes Mellitus

open access: yesInternational Journal of Vascular Medicine
Conclusions: In summary, our findings suggest that the risk of PAD is positively correlated with the number of MetS components in patients with T2DM, especially among younger patients and older patients. Additionally, the positive association between the
Xiaotong Feng   +7 more
doaj   +1 more source

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