Results 281 to 290 of about 456,798 (336)

Reproductive impact of immune checkpoint inhibitor therapy in women with melanoma. [PDF]

F S Rep
Rhodes Q, Woodard TL, Detti L, Roth M, Shott S, McQuade J, McKenzie LJ.   +6 more
europepmc   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Immune checkpoint inhibitor-induced hemophagocytic lymphohistiocytosis in lung cancer: a case series. [PDF]

Explor Target Antitumor Ther
Khan AW, Chandra S, Mahadevia H, Subramanian J, Ponvilawan B, Bansal D.   +5 more
europepmc   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Use of Apremilast for the Treatment of Immune Checkpoint Inhibitor Psoriasis and Psoriatic Arthritis. [PDF]

Arthritis Care Res (Hoboken)
Ghosh N, Reid P, Sparks JA, McCarter K, Ge K, Bass AR.   +5 more
europepmc   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Associations Between Anxiety or Depression Diagnosis and Immune Checkpoint Inhibitor Outcomes. [PDF]

Cancer Med
Derry-Vick H, Shah NJ, Ahn J, DeAgresta B, Della Pia A, Zaemes JP, Pascual L, Arias-Orozco N, Zemel R, Sidarous G, Serzan M, Lev-Ari S, Alaoui A, Marki A, Nguyen K, Charalampous C, Rahman I, Wilkins O, Girgis M, Sridhar A, Adams D, Pecora AL, Atkins MB, Ip A.   +23 more
europepmc   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Plasma Fibrinogen Predicts Response to Immune Checkpoint Inhibitor by Inflammatory Tumor Microenvironment in Esophageal Cancer. [PDF]

Cancer Med
Ho K, Matsuda S, Booka E, Soneda W, Okui J, Hoshino S, Takeuchi M, Fukuda K, Horie S, Saito Y, Kogure Y, Kawakubo H, Hara K, Okita H, Kataoka K, Sekine S, Takeuchi H, Kitagawa Y.   +17 more
europepmc   +1 more source

Immune Checkpoint Inhibitor-induced Hepatitis, an Emerging Issue in Precision Cancer Therapy Era: A Narrative Literature Review. [PDF]

Rambam Maimonides Med J
Adiwinata R, Tanadi C, Pajala FB, Tandarto K, Stella MM, Tenggara JB, Gunarsa RG, Simadibrata P, Siregar L, Nababan SHH, Sulaiman BS, Hasan I, Lesmana CRA, Sudoyo AW.   +13 more
europepmc   +1 more source