Research progress of the immunosuppressive tumor microenvironment in multiple myeloma
Multiple myeloma (MM) is a hematological malignancy originating from the immune system, and the immune microenvironment plays a pivotal role in its pathogenesis and progression.
Yue WANG, Peng LIU
doaj +1 more source
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li +11 more
wiley +1 more source
Running on Exhaustion: Pathogen Burden, Immune Dysregulation, and Endothelial Activation After Coronary Artery Bypass Graft Surgery [PDF]
Pamela S. Miller
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Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
X-linked Disorder Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (ipex) In Brazilian Twins Brothers - A Report [PDF]
Jyunko Tanno +9 more
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Immune Dysregulation in Endometriomas: Implications for Inflammation
The most common manifestation of endometriosis, a condition characterized by the presence of endometrial-like tissue outside of the uterus, is the endometrioma, a cystic ovarian lesion. It is a commonly occurring condition associated with chronic pelvic pain exacerbated prior to and during menstruation, as well as infertility. The exact pathomechanisms
Izabela Dymanowska-Dyjak +7 more
openaire +2 more sources
Biosupercapacitors for Human‐Powered Electronics
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim +7 more
wiley +1 more source
Role of miRNAs in Apoptosis Pathways of Immune Cells in Systemic Lupus Erythematosus
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by dysregulated immune responses and multi‐organ involvement.
Amin Azizan +5 more
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Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart [PDF]
Katarzyna A. Cieslik +5 more
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Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source

