Results 151 to 160 of about 2,310,452 (384)

Immune dysregulation orchestrated by high-salt diet: Mechanistic insights into disease pathogenesis [PDF]

, 2023
Li Chen, Yixiao chen, Xile Peng, Zhi-xuan Chen, Junrui Tang, Jie Wang, Kaidi nie, Luming Qi, Tingting Deng, Xia Li-na   +9 more
openalex   +1 more source

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

Cell Host and Microbe, 2020
E. Giamarellos‐Bourboulis, M. Netea, N. Rovina, Karolina Akinosoglou, A. Antoniadou, N. Antonakos, G. Damoraki, T. Gkavogianni, M. Adami, P. Katsaounou, Maria Ntaganou, Magdalini Kyriakopoulou, G. Dimopoulos, I. Koutsodimitropoulos, D. Velissaris, Panagiotis Koufargyris, A. Karageorgos, K. Katrini, Vasileios Lekakis, M. Lupșe, A. Kotsaki, George Renieris, Danai Theodoulou, V. Panou, E. Koukaki, N. Koulouris, C. Gogos, A. Koutsoukou   +27 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. [PDF]

, 2019
How pathogenic cluster of differentiation 4 (CD4) T cells in rheumatoid arthritis (RA) develop remains poorly understood. We used Nur77-a marker of T cell antigen receptor (TCR) signaling-to identify antigen-activated CD4 T cells in the SKG mouse model ...
Ashouri, Judith F, Chen, Yiling, Cheng, Debra A, Hansen, Erik, Hsu, Lih-Yun, Lattanza, Lisa, Rychkov, Dmitry, Sirota, Marina, Weiss, Arthur, Yu, Steven, Zikherman, Julie   +10 more
core  

Supplementary Figure 1 from Local and Systemic Immune Dysregulation Alters Glioma Growth in Hyperglycemic Mice

, 2023
Ian Y. Zhang, Hui Zhou, Huili Liu, Leying Zhang, Hang Gao, Shunan Liu, Yan‐Yan Song, Darya Alizadeh, Hongwei Yin, Raju Pillai, Behnam Badie   +10 more
openalex   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Cord serum cytokines at birth and children's trajectories of mood dysregulation symptoms from 3 to 8 years: The EDEN birth cohort

Brain, Behavior, & Immunity - Health
There is growing evidence that in utero imbalance immune activity plays a role in the development of neurodevelopmental and psychiatric disorders in children.
Marie Herbein, Susana Barbosa, Ophélie Collet, Olfa Khalfallah, Marie Navarro, Marion Bailhache, Nicolas IV, Bruno Aouizerate, Anne-Laure Sutter-Dallay, Muriel Koehl, Lucile Capuron, Pierre Ellul, Hugo Peyre, Judith Van der Waerden, Maria Melchior, Sylvana Côté, Barbara Heude, Nicolas Glaichenhaus, Laetitia Davidovic, Cedric Galera   +19 more
doaj   +1 more source

Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach.

International Immunopharmacology, 2022
Mansur Aliyu, F. Zohora, A. Anka, Kashif Ali, S. Maleknia, Mohammad Saffarioun, G. Azizi   +6 more
semanticscholar   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Down Syndrome in Children: A Primary Immunodeficiency with Immune Dysregulation

Children
Background: The multisystemic features of Down syndrome (DS) in children are accompanied by immunodeficiency, making them susceptible to infections and immune dysregulation with autoimmune, allergic, inflammatory, and hematological complications.
Aleksandra Szczawińska-Popłonyk, Natalia Popłonyk, Karina Awdi   +2 more
doaj   +1 more source