National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Immune Dysregulation and Pathobiology Working Group Report [PDF]
Juan Gea‐Banacloche+11 more
openalex +1 more source
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz+14 more
wiley +1 more source
Monocytes and parturition: Linking prolonged labor to immune dysregulation. [PDF]
Obeagu EI.
europepmc +1 more source
Diffuse traumatic brain injury induces prolonged immune dysregulation and potentiates hyperalgesia following a peripheral immune challenge [PDF]
Rachel K. Rowe+8 more
openalex +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
Interplay of hypoxia, immune dysregulation, and metabolic stress in pathophysiology of type 1 diabetes. [PDF]
Mittal R+3 more
europepmc +1 more source
Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian+10 more
wiley +1 more source
Diabetic Foot Ulcers: Pathophysiology, Immune Dysregulation, and Emerging Therapeutic Strategies. [PDF]
Dawi J+8 more
europepmc +1 more source