Results 11 to 20 of about 2,310,452 (384)

Immune Dysregulation in Pediatric Common Variable Immunodeficiency: Implications for the Diagnostic Approach

Frontiers in Pediatrics, 2022
Infections and infectious complications are hallmarks of common variable immunodeficiency (CVID) and the leading cause of morbidity and mortality in affected patients at any age.
Aleksandra Szczawińska-Popłonyk, Katarzyna Ta̧polska-Jóźwiak, Eyal Schwartzmann, Natalia Popłonyk   +3 more
doaj   +2 more sources

Immune dysregulation and system pathology in COVID-19

Virulence, 2021
The coronavirus disease 19 (COVID-19) caused by the novel coronavirus known as SARS-CoV-2 has caused a global public health crisis. As of 7 January 2021, 87,640,402 confirmed cases and 1,891,692 mortalities have been reported worldwide.
Muhammad Jamal, Hina Iqbal Bangash, Maria Habiba, Yufei Lei, Tian Xie, Jiaxing Sun, Zimeng Wei, Zixi Hong, Liang Shao, Qiuping Zhang   +9 more
doaj   +2 more sources

Re-emerging concepts of immune dysregulation in autism spectrum disorders [PDF]

Frontiers in Psychiatry, 2022
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by communication and social interaction deficits, and by restricted interests and stereotyped, repetitive behavior patterns.
Alina Erbescu, Sorina Mihaela Papuc, Magdalena Budișteanu, Aurora Arghir, Monica Neagu   +4 more
openalex   +2 more sources

COVID-19 disease and immune dysregulation

Best Practice & Research Clinical Haematology, 2022
The SARS-CoV-2 virus has complex and divergent immune alterations in differing hosts and over disease evolution. Much of the nuanced COVID-19 disease immune dysregulation was originally dominated by innate cytokine changes, which has since been replaced with a more complex picture of innate and adaptive changes characterized by simultaneous ...
Ethan Davitt, Colin Davitt, M. Mazer, S. Areti, R. Hotchkiss, Kenneth E. Remy   +5 more
semanticscholar   +3 more sources

Body talk: Correlates of gut-immune dysregulation phenotypes in people living with HIV who use methamphetamine [PDF]

Brain, Behavior, & Immunity - Health
Background: Microbial translocation, immune activation, inflammation, and dysregulated metabolism of neurotransmitter precursors are interacting pathophysiologic processes linked to neuropsychiatric comorbidities and faster HIV disease progression.
Wilson Vincent, Annesa Flentje, Benjamin S. Dominguez, Robert H. Paul, Savita Pahwa, Suresh Pallikkuth, Margaret Roach, Dietmar Fuchs, Samantha E. Dilworth, Torsten B. Neilands, Peter W. Hunt, Gowri Sunder, Cody Lentz, Sydney Telaak, Adam W. Carrico   +14 more
doaj   +2 more sources

Immune Dysregulation in Children With Down Syndrome

Frontiers in Pediatrics, 2020
Down syndrome (DS) is the most common genetic syndrome associated with immune defects. The extent of immune dysregulation in DS is substantial, spanning the innate and adaptive systems and including anomalies in: T and B cells, monocytes, neutrophil ...
Dean Huggard, Dean Huggard, Dean Huggard, Dean Huggard, Derek G. Doherty, Derek G. Doherty, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy, Eleanor J. Molloy   +10 more
doaj   +2 more sources

Refractory immune thrombocytopenia: Lessons from immune dysregulation disorders

Frontiers in Medicine, 2022
Giorgio Costagliola, Rita Consolini
doaj   +3 more sources

Immune‐dysregulation harnessing in myeloid neoplasms

Cancer Medicine
Myeloid malignancies arise in bone marrow microenvironments and shape these microenvironments in favor of malignant development. Immune suppression is one of the most important stages in myeloid leukemia progression.
Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi   +5 more
doaj   +3 more sources

Autoimmunity and Inborn Errors of Immunity: Two Faces of the Same Coin! [PDF]

Pediatric Infectious Disease, 2022
Autoimmune disorders are a heterogeneous group of disorders characterized by immune dysregulation and are associated with a loss of tolerance to self-antigens.
Neha Singh, Sagar Bhattad
doaj   +1 more source

Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction

Nature Communications, 2021
Multi-inflammatory syndrome in children (MIS-C) can be associated with SARS-CoV-2 infection but can also be similar to other inflammatory syndromes. Here the authors characterise the plasma proteome phenotype in MIS-C and compare to other SARS-CoV-2 ...
Caroline Diorio, Rawan Shraim, Laura A. Vella, Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Scott W. Canna, Sarah E. Henrickson, Kevin O. McNerney, Frances Balamuth, Chakkapong Burudpakdee, Jessica Lee, Tomas Leng, Alvin Farrel, Michele P. Lambert, Kathleen E. Sullivan, E. John Wherry, David T. Teachey, Hamid Bassiri, Edward M. Behrens   +19 more
doaj   +1 more source