Results 191 to 200 of about 236,691 (313)

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions [PDF]

, 2018
Brian Crucian, Alexander Choukér, Richard J. Simpson, Satish Mehta, Gailen D. Marshall, Scott M. Smith, Sara R. Zwart, Martina Heer, С. А. Пономарев, Alexandra Whitmire, Jean P. Frippiat, Grace L. Douglas, Hernán Lorenzi, Judith‐Irina Buchheim, George Makedonas, Geoffrey S. Ginsburg, C. Mark Ott, Duane L. Pierson, Stephanie Krieger, Natalie Baecker, Clarence F. Sams   +20 more
openalex   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

Nucleic Acid Diversity in cGAS-STING Pathway Activation and Immune Dysregulation. [PDF]

Biomedicines
Guo J, Lu M, Wang C, Wang D, Ma T.
europepmc   +1 more source

Dysregulation of lipidomic profile and antiviral immunity in response to hyaluronan in patients with severe asthma

, 2016
Milena Sokołowska, Li‐Yuan Chen, Yueqin Liu, Asunción Martínez‐Antón, Carolea Logun, Sara Alsaaty, Rosemarie A. Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron M. Armando, Edward A. Dennis, Stewart J. Levine, James H. Shelhamer   +13 more
openalex   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source

Immune Dysregulation and Prognosis in Sepsis: Insights From a Posttranslational Perspective. [PDF]

Hum Mutat
Ye Y, Chen Q, Wu D, Yu G, Liu J, Li Y, Xu Z, Lin L.   +7 more
europepmc   +1 more source

Managing immune dysregulation resulting from immune checkpoint inhibitors: impact of the ASCO guidelines and key take-homes for immunologists [PDF]

, 2018
Sang T. Kim, María E. Suarez‐Almazor
openalex   +1 more source

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

Editorial: Microbial dysbiosis and immune dysregulation in periodontitis and peri-implantitis. [PDF]

Front Cell Infect Microbiol
Morandini AC, Gangula PR, Li Y, Deng K.
europepmc   +1 more source

Mechanism-Based Strategies for the Management of Autoimmunity and Immune Dysregulation in Primary Immunodeficiencies

, 2016
Jolán E. Walter, Jocelyn R. Farmer, Zsófia Földvári, Troy R. Torgerson, Megan A. Cooper   +4 more
openalex   +1 more source