Results 211 to 220 of about 2,310,452 (384)

Systematic profiling reveals hepatic immune and metabolic dysregulation in DNASE1L3-deficient mice

Liangchen Lei, Jianshe Yu, Bo Zhang, Pengpeng Liu, Zhuo Meng, Youai Song, Jianwei Lan, Binjie Li, Quanyan Liu   +8 more
openalex   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

Data Sheet 1_Integrative scRNA-seq and transcriptomic analysis initially reveals monocyte/macrophage activation drives EV-A71-induced immune dysregulation and neural injury in severe HFMD.docx

Muqi Wang (18535171), Meng Zhang (154027), Huiling Deng (4427161), Yufeng Zhang (195768), Chenrui Liu (13561118), Yuan Chen (9740), Chuting Zhang (12478758), Wen Zhang (7555), Xiaoli Jia (399719), Shuangsuo Dang (399716), Yaping Li (399717)   +10 more
openalex   +1 more source

Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation

, 2020
Louie Mar A. Gangcuangco, Brooks I. Mitchell, Chathura Siriwardhana, Lindsay B. Kohorn, Glen M. Chew, Scott Bowler, Kalpana J. Kallianpur, Dominic C. Chow, Lishomwa C. Ndhlovu, Mariana Gerschenson, Cecilia M. Shikuma   +10 more
openalex   +2 more sources

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Regulatory T Cell Dysregulation in Vitiligo: A Meta-Analysis and Systematic Review of Immune Mechanisms and Therapeutic Perspectives

Gabriela Lerner, Maria Nikolaou, Corinne I. Stoffel, Eloi Schmauch, Thomas Kündig, Thierry Passeron, Julien Sénéschal, Nanja Van Geel, Ulrike Held, Antonios G A Kolios   +9 more
openalex   +1 more source

UK Experience Of Treosulfan-Based Conditioning Regimens In Children With Primary Immunodeficiency Or Severe Immune Dysregulation [PDF]

, 2010
Mary Slatter, K. S. Rao, Persis Amrolia, Terence Flood, Mario Abinun, A J Cant, Sophie Hambleton, Nicholas Goulden, Andrew R. Gennery, Paul Veys   +9 more
openalex   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]

Mediators Inflamm
Farahani H, Kokhaei P, Ganji A, Mosayebi G, Ghazavi A.   +4 more
europepmc   +1 more source

Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease

, 2014
Xiaorong Xu
openalex   +2 more sources