Results 231 to 240 of about 215,248 (308)

A Novel Description of Immunodeficiency and Immune Dysregulation in a 14-Year-Old Girl with Noonan Syndrome 13. [PDF]

J Clin Immunol
Tabassum S, Grün S, Molloy B, Jones E, Buckley PG, Amet R, McElligott AM, Doherty DG, Ehl S, Leahy TR.   +9 more
europepmc   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

Advanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu, Ding Yang, Jingsen Ji, Gengyou Li, Haoting Chen, Yuying Yao, Chenxing Fu, Fangling Liao, Jinzhao Liu, Yaming Zhang, Zechuan Li, Jing Zhang, Huike Ma, Jingxia Zhao, Ying‐Shi Sun, Weisheng Guo, Weiping Wang   +16 more
wiley   +1 more source

Chronic suppurative otitis media: disrupted host-microbial interactions and immune dysregulation. [PDF]

Front Immunol
Yuan VG, Xia A, Santa Maria PL.
europepmc   +1 more source

Dysregulation of immune mechanisms as a basic cause of rheumatoid arthritis.

, 2018
Э.Ж. Битанова, А.С. Тарабаева, D. Erbolat, D.V. Goryacheva   +3 more
openalex   +1 more source

STAT6 Activation Exacerbates Ferroptosis in Airway Epithelium by Inhibiting PRKN‐Mediated Mitophagy in Pulmonary Fibrosis

Advanced Science, EarlyView.
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang, Guangbin Huang, Tao Zhang, Yi Ling, Junyu Jiang, Dingyuan Du, Yu Ma, Shasha Tao   +7 more
wiley   +1 more source

Palmitoylation-driven immune dysregulation and prognostic signature in low-grade glioma: a multi-omics and functional validation study. [PDF]

Front Pharmacol
Wang Z, Yu T, Liu Y, Wu Y, Hu J.
europepmc   +1 more source

Additional file 3: of Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis

, 2018
Madhusudan Grover, Simon J. Gibbons, Asha Nair, Cheryl E. Bernard, Adeel Zubair, Seth T. Eisenman, Laura Wilson, Laura Miriel, Pankaj J. Pasricha, Henry P. Parkman, Irene Sarosiek, Richard W. McCallum, Kenneth L. Koch, Thomas Abell, William J. Snape, Braden Kuo, Robert J. Shulman, Travis J. McKenzie, Todd A. Kellogg, Michael L. Kendrick, James Tonascia, Frank A. Hamilton, Gianrico Farrugia   +22 more
openalex   +2 more sources

Asthma and the Dysregulated Immune Response to Rhinovirus

American Journal of Respiratory and Critical Care Medicine, 2020
openaire   +3 more sources

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source