Results 281 to 290 of about 236,691 (313)
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Immunodeficiency and disorders of immune dysregulation
Pediatric Allergy and Immunology, 2020AbstractThe spectrum of clinical features associated with primary immune deficiency disorders (PIDs) has broadened due to the recent identification of many novel causative genes. Patients present with increased susceptibility to infections in addition to significant immune dysregulation, often leading to multiple autoimmunity, lymphoproliferation, and ...
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Current Opinion in Allergy and Clinical Immunology, 2002
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome is a fatal syndrome of overwhelming autoimmunity. Recent identification of FOXP3 as the causative gene and realization that this same gene defect occurs in the mutant mouse Scurfy has yielded new insights and hopes of unraveling the mechanism of autoimmunity in this and possibly ...
Troy R. Torgerson, Hans D. Ochs
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Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome is a fatal syndrome of overwhelming autoimmunity. Recent identification of FOXP3 as the causative gene and realization that this same gene defect occurs in the mutant mouse Scurfy has yielded new insights and hopes of unraveling the mechanism of autoimmunity in this and possibly ...
Troy R. Torgerson, Hans D. Ochs
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Asthma: The importance of dysregulated barrier immunity
European Journal of Immunology, 2013Chronic asthma is an inflammatory disease of the airway wall that leads to bronchial smooth muscle hyperreactivity and airway obstruction, caused by inflammation, goblet cell metaplasia, and airway wall remodeling. In response to allergen presentation by airway DCs, T‐helper lymphocytes of the adaptive immune system control many aspects of the disease ...
Bart N. Lambrecht, Hamida Hammad
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MRI investigation of immune dysregulation in schizophrenia
Current Opinion in Psychiatry, 2019Immune dysregulation has been suggested as a pathophysiological pathway in schizophrenia. MRI could aid in investigating this pathological process in more detail. This review aims to provide an overview of recent MRI findings of immune dysregulation in schizophrenia. In addition, we discuss the potential of more recently developed MRI techniques.Subtle
René C.W. Mandl +4 more
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The Immune System and Its Dysregulation with Aging
2019Aging leads to numerous changes that affect all physiological systems of the body including the immune system, causing greater susceptibility to infectious disease and contributing to the cardiovascular, metabolic, autoimmune, and neurodegenerative diseases of aging.
Müller, L. +2 more
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Immune dysregulation in bipolar disorder
Journal of Affective DisordersBipolar disorder is a debilitating mood disorder associated with a high risk of suicide and characterized by immune dysregulation. In this study, we used a multi-faceted approach to better distinguish the pattern of dysregulation of immune profiles in individuals with BD.We analyzed peripheral blood mononuclear cells (bipolar disorder N = 39, control N
Benney M R, Argue +11 more
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Immune dysregulation and dyserythropoiesis in MDS
2010The myelodysplastic syndromes (MDS) are clonal disorders characterised by ineffective haematopoiesis with high risk of leukaemia progression. The relevance of immune-dysregulation for emergence, dominance and progression of dysplastic clones has been suggested, but valuable criteria to obtain insight into these connections are lacking.
ALFINITO, FIORELLA +8 more
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Cervical cancer prevention and control in women living with human immunodeficiency virus
Ca-A Cancer Journal for Clinicians, 2021Philip E Castle, Vikrant V Sahasrabuddhe
exaly
Emerging Concepts in Immune Dysregulation
Rheumatic Disease Clinics of North America, 2023openaire +4 more sources