Results 21 to 30 of about 236,691 (313)
Immune dysregulation in immunoglobulin G4–related disease
Japanese Dental Science Review, 2023 (IgG4-RD) is an immune-mediated fibrotic disorder characterized by severe resolution of inflammation and dysregulation of wound healing. IgG4-RD has been considered a unique disease since 2003, and significant progress has been achieved in the ...
Takashi Maehara +2 more
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Immune dysregulation and system pathology in COVID-19
Virulence, 2021 The coronavirus disease 19 (COVID-19) caused by the novel coronavirus known as SARS-CoV-2 has caused a global public health crisis. As of 7 January 2021, 87,640,402 confirmed cases and 1,891,692 mortalities have been reported worldwide.
Muhammad Jamal +9 more
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Glyphosate induces immune dysregulation in honey bees
Animal Microbiome, 2022 Background Similar to many other animals, the honey bee Apis mellifera relies on a beneficial gut microbiota for regulation of immune homeostasis. Honey bees exposed to agrochemicals, such as the herbicide glyphosate or antibiotics, usually exhibit ...
Erick V. S. Motta +2 more
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Mucosal Immune System Dysregulation in the Pathogenesis of IgA Nephropathy
Biomedicines, 2022 The mucosal immune system, via a dynamic immune network, serves as the first line of defense against exogenous antigens. Mucosal immune system dysregulation is closely associated with the pathogenesis of immunoglobulin A nephropathy (IgAN), as ...
Toshiki Kano +11 more
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Dysregulation of Systemic Immunity in Aging and Dementia [PDF]
Frontiers in Cellular Neuroscience, 2021 Neuroinflammation and the tissue-resident innate immune cells, the microglia, respond and contribute to neurodegenerative pathology. Although microglia have been the focus of work linking neuroinflammation and associated dementias like Alzheimer’s Disease, the inflammatory milieu of brain is a conglomerate of cross-talk amongst microglia, systemic ...
Jenny Lutshumba +7 more
openaire +4 more sources
Cell Reports, 2019 Summary: People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions.
Katherine A. Waugh +22 more
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Dysregulation of immune response in otitis media [PDF]
Expert Reviews in Molecular Medicine, 2021 Abstract Objective Otitis media (OM) is a common reason for children to be prescribed antibiotics and undergo surgery but a thorough understanding of disease mechanisms is lacking. We evaluate the evidence of a dysregulated immune response in the pathogenesis of OM.
Michael W. Mather +6 more
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Immune dysregulation in Down syndrome
Nature Reviews Immunology, 2023 The immune system in individuals with Down syndrome is characterized by steady state increases in cytokine expression, T cell activation, atypical B cell responses and the presence of numerous autoantibodies.
openaire +2 more sources
Immune System Abnormalities in Schizophrenia: An Integrative View and Translational Perspectives
Frontiers in Psychiatry, 2022 The immune system is generally known to be the primary defense mechanism against pathogens. Any pathological conditions are reflected in anomalies in the immune system parameters.
Evgeny A. Ermakov +5 more
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From Immune Dysregulations to Therapeutic Perspectives in Myelodysplastic Syndromes: A Review
Diagnostics, 2021 The pathophysiology of myelodysplastic syndromes (MDSs) is complex and often includes immune dysregulation of both the innate and adaptive immune systems.
Thibault Comont +2 more
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