Immune dysregulation in primary immune thrombocytopenia patients [PDF]
Hematology, 2018 To explore the immunological abnormalities in patients with primary immune thrombocytopenia (ITP), and analyze its relationship with treatment.Proportion of different immune cell subsets were detected in the peripheral blood of 124 ITP patients at different time points and 45 normal controls by flow cytometry.
Jiakui, Zhang +13 more
openaire +2 more sources
The Role of ncRNAs in the Immune Dysregulation of Preeclampsia
International Journal of Molecular Sciences, 2023 The main complications causing practically 75% of all maternal deaths are severe bleeding, infections, and high blood pressure during pregnancy (preeclampsia (PE) and eclampsia).
C. Mora-Palazuelos +7 more
semanticscholar +1 more source
Immune dysregulation as a driver of idiopathic pulmonary fibrosis.
Journal of Clinical Investigation, 2021 Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide, reducing their quality of life and leading to death from respiratory failure within years of diagnosis.
K. Shenderov +3 more
semanticscholar +1 more source
Immune Dysregulation in Acute SARS-CoV-2 Infection
Pathogens and Immunity, 2023 Introduction: Neutralizing antibodies have been shown to develop rapidly following SARS-CoV-2 infection, specifically against spike (S) protein, where cytokine release and production is understood to drive the humoral immune response during acute ...
Lauren Grimm +10 more
doaj +1 more source
Age-related changes to macrophages are detrimental to fracture healing in mice. [PDF]
, 2020 The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
Brazina, Sloane +8 more
core +2 more sources
Novel Discoveries in Immune Dysregulation in Inborn Errors of Immunity
Frontiers in Immunology, 2021 With the expansion of our knowledge on inborn errors of immunity (IEI), it gradually becomes clear that immune dysregulation plays an important part.
Anwen Ren +10 more
doaj +1 more source
Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
, 2016 Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core +1 more source
miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS [PDF]
, 2019 ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
et al,, Mar, Soe
core +6 more sources
The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. [PDF]
, 2019 Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades.
Chang, Eric Y +7 more
core +1 more source
Gestational Diabetes Mellitus and Maternal Immune Dysregulation: What We Know So Far
International Journal of Molecular Sciences, 2021 Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance with onset or first recognition during pregnancy, and is characterized by ...
Colm J McElwain +2 more
semanticscholar +1 more source