Stress and cancer: The mechanisms of immune dysregulation and management
Frontiers in Immunology, 2022 Advances in the understanding of psychoneuroimmunology in the past decade have emphasized the notion that stress and cancer are interlinked closely.
Yixin Liu +5 more
semanticscholar +1 more source
Lentivirus-induced immune dysregulation [PDF]
Veterinary Immunology and Immunopathology, 2008 FIV/HIV infections are associated with an early robust humoral and cellular anti-viral immune response followed by a progressive immune suppression that eventually results in AIDS. Several mechanisms responsible for this immune dysfunction have been proposed including cytokine dysregulation, immunologic anergy and apoptosis, and inappropriate ...
Mary B. Tompkins, Wayne A. F. Tompkins
openaire +2 more sources
Microvascular significance of TGF-β axis activation in COVID-19
Frontiers in Cardiovascular Medicine, 2023 As 2023 approaches, the COVID-19 pandemic has killed millions. While vaccines have been a crucial intervention, only a few effective medications exist for prevention and treatment of COVID-19 in breakthrough cases or in unvaccinated or immunocompromised ...
Lauren M. Arguinchona +6 more
doaj +1 more source
A nonconservative kinetic model under the action of an external force field for modeling the medical treatment of autoimmune response [PDF]
, 2023 In this paper, we develop a new nonconservative kinetic framework to be applied for the study of immune system dysregulation. From the modeling viewpoint, the new kinetic model regards a system, composed of stochastically interacting agents, under the action of an eternal force field.
arxiv +1 more source
The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. [PDF]
, 2019 Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades.
Chang, Eric Y +7 more
core +1 more source
Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
, 2016 Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core +1 more source
Gestational Diabetes Mellitus and Maternal Immune Dysregulation: What We Know So Far
International Journal of Molecular Sciences, 2021 Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance with onset or first recognition during pregnancy, and is characterized by ...
Colm J McElwain +2 more
semanticscholar +1 more source
Genetics of Immune Dysregulation and Cancer Predisposition: Two Sides of the Same Coin
Clinical and Experimental Immunology, 2022 Approximately 10% of cancers have a hereditary predisposition. However, no genetic diagnosis is available in 60%-80% of familial cancers. In some of these families, immune dysregulation-mediated disease is frequent.
Sigal Matza Porges, O. Shamriz
semanticscholar +1 more source
Dysregulation of Systemic Immunity in Aging and Dementia [PDF]
Frontiers in Cellular Neuroscience, 2021 Neuroinflammation and the tissue-resident innate immune cells, the microglia, respond and contribute to neurodegenerative pathology. Although microglia have been the focus of work linking neuroinflammation and associated dementias like Alzheimer’s Disease, the inflammatory milieu of brain is a conglomerate of cross-talk amongst microglia, systemic ...
Jenny Lutshumba +7 more
openaire +4 more sources
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]
, 2019 ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory +31 more
core +5 more sources