Results 221 to 230 of about 1,602,221 (268)
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Microglia: Immune and non-immune functions
Immunity, 2021As resident macrophages of the central nervous system (CNS), microglia are associated with diverse functions essential to the developing and adult brain during homeostasis and disease. They are aided in their tasks by intricate bidirectional communication with other brain cells under steady-state conditions as well as with infiltrating peripheral ...
Borst, Katharina +2 more
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Pediatric Clinics of North America, 2000
The innate and the adaptive immune systems have evolved to provide a rapid and specific means for protecting hosts against the many microbes experienced over a lifetime. These two immune responses interact cooperatively to enhance the host defense. Defects in either of these two pathways can have devastating consequences, as evidenced [figure: see text]
T A, Fleisher, J J, Bleesing
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The innate and the adaptive immune systems have evolved to provide a rapid and specific means for protecting hosts against the many microbes experienced over a lifetime. These two immune responses interact cooperatively to enhance the host defense. Defects in either of these two pathways can have devastating consequences, as evidenced [figure: see text]
T A, Fleisher, J J, Bleesing
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Nursing Standard, 2013
This article, which forms part of the life sciences series, explores the function of the immune system. It is important that nurses understand how the immune system works and its role in the prevention of infection. Innate and adaptive immunity are described and the differences between these two types of immune response are discussed.
Charles, Hendry +3 more
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This article, which forms part of the life sciences series, explores the function of the immune system. It is important that nurses understand how the immune system works and its role in the prevention of infection. Innate and adaptive immunity are described and the differences between these two types of immune response are discussed.
Charles, Hendry +3 more
openaire +2 more sources
Clinics in Dermatology, 2001
The skin comprises approximately 1.5 to 2 m 2 of the average human’s surface and represents the largest organ in the body, providing the principal physical barrier to the environment.1 In addition, the skin functions as the most peripheral component of the immune system and initiates a primary immune response to foreign antigen (Ag).
C, Debenedictis +4 more
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The skin comprises approximately 1.5 to 2 m 2 of the average human’s surface and represents the largest organ in the body, providing the principal physical barrier to the environment.1 In addition, the skin functions as the most peripheral component of the immune system and initiates a primary immune response to foreign antigen (Ag).
C, Debenedictis +4 more
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Critical Reviews in Toxicology, 2006
The heavy metal lead is a widely deposited environmental toxicant known to impact numerous physiological systems, including the reproductive, neurological, hepatic, renal, and immune systems. Studies illustrating the capacity of lead to impair immune function and/or host resistance to disease date back to at least the 1960s.
Rodney R, Dietert +1 more
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The heavy metal lead is a widely deposited environmental toxicant known to impact numerous physiological systems, including the reproductive, neurological, hepatic, renal, and immune systems. Studies illustrating the capacity of lead to impair immune function and/or host resistance to disease date back to at least the 1960s.
Rodney R, Dietert +1 more
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Clinics in Dermatology, 2011
The skin, the body's largest organ, helps to secure the integrity of the host and, at the same time, allows the individual to communicate with the outside world. This finely tuned balance between protection from harmful pathogens (mostly microorganisms) and bidirectional signal exchange is provided by a network of structural, cellular, and molecular ...
Christine, Bangert +2 more
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The skin, the body's largest organ, helps to secure the integrity of the host and, at the same time, allows the individual to communicate with the outside world. This finely tuned balance between protection from harmful pathogens (mostly microorganisms) and bidirectional signal exchange is provided by a network of structural, cellular, and molecular ...
Christine, Bangert +2 more
openaire +2 more sources
Thrombosis and Haemostasis, 2014
SummaryThis review collects evidence about immune and inflammatory functions of platelets from a clinician’s point of view. A focus on clinically relevant immune functions aims at stimulating further research, because the complexity of platelet immunity is incompletely understood and not yet translated into patient care.
Bode, Christoph +2 more
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SummaryThis review collects evidence about immune and inflammatory functions of platelets from a clinician’s point of view. A focus on clinically relevant immune functions aims at stimulating further research, because the complexity of platelet immunity is incompletely understood and not yet translated into patient care.
Bode, Christoph +2 more
openaire +3 more sources
2012
Notch2 is expressed in many cell types of most lineages in the hematolymphoid compartment and has specific roles in differentiation and function of various immune cells. Notch2 is required for development of splenic marginal zone B cells and regulates differentiation of dendritic cells (DCs) in the spleen.
Mamiko, Sakata-Yanagimoto +1 more
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Notch2 is expressed in many cell types of most lineages in the hematolymphoid compartment and has specific roles in differentiation and function of various immune cells. Notch2 is required for development of splenic marginal zone B cells and regulates differentiation of dendritic cells (DCs) in the spleen.
Mamiko, Sakata-Yanagimoto +1 more
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Glia, 2001
AbstractAstrocytes are the major glial cell within the central nervous system (CNS) and have a number of important physiological properties related to CNS homeostasis. The aspect of astrocyte biology addressed in this review article is the astrocyte as an immunocompetent cell within the brain.
Y, Dong, E N, Benveniste
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AbstractAstrocytes are the major glial cell within the central nervous system (CNS) and have a number of important physiological properties related to CNS homeostasis. The aspect of astrocyte biology addressed in this review article is the astrocyte as an immunocompetent cell within the brain.
Y, Dong, E N, Benveniste
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Anaesthetics and immune function
Current Opinion in Anaesthesiology, 2001Surgical trauma and anaesthetics may cause immune suppression, predisposing patients to postoperative infections. Furthermore, stress such as surgery and pain per se is associated with immune suppression which, in animal models, leads to an increased susceptibility to infection and tumour spread.
I, Kelbel, M, Weiss
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