Results 211 to 220 of about 1,249,521 (280)

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

KDM4 Regulates the Glycolysis of Hemocytes in the Immune Priming of Eriocheir sinensis. [PDF]

open access: yesInt J Mol Sci
Zhao X   +9 more
europepmc   +1 more source

Phase‐Pure and Size‐Tunable Tin Halide Perovskite Quantum Dots

open access: yesAdvanced Materials, EarlyView.
A trioctylphosphine oxide modulated protocol allows for the synthesis and study of the optical properties of a broad library of tin halide perovskite quantum dots across multiple A‐ and X‐site compositions with precise size tuning while eliminating unwanted 2D phases.
Ole F. Dressler   +7 more
wiley   +1 more source

Circulating EV miRNA Cargo in Glioblastoma Patients Is Associated with Distinct Gene Expression Signatures in Peripheral Immune Cells, Suggesting an Early, Compartment-Specific Immune Priming State. [PDF]

open access: yesBiomedicines
Popovic-Vukovic M   +10 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

open access: yesAdvanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi   +5 more
wiley   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

open access: yesAdvanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma   +15 more
wiley   +1 more source

Prophylactic immune priming with heat-killed <i>Lacticaseibacillus rhamnosus</i> combined with therapeutic <i>Lactiplantibacillus plantarum</i> cell-free supernatant protects against <i>Pseudomonas aeruginosa</i> lung infection in mice. [PDF]

open access: yesFront Immunol
Gong W   +10 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

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