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Immunological consequences of "immune reconstitution therapy" in multiple sclerosis: A systematic review.

Autoimmunity Reviews, 2020
Immune reconstitution therapy (IRT) is an emerging concept for the treatment of multiple sclerosis (MS) that is given intermittently and can induce long-term remission of MS that is sustained in treatment-free periods.
J. Sellner, P. Rommer
semanticscholar   +1 more source

Immune reconstitution inflammatory syndrome

International Journal of STD & AIDS, 2009
Antiretroviral therapy (ART) inhibits HIV replication, allowing recovery of CD4+ T cell numbers and the restoration of immune function; its introduction has led to improved outcomes for individuals with HIV infection. However, it has been observed that some individuals responding to ART experience a clinical deterioration with symptoms and signs of an
J W T, Elston, H, Thaker
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Immune reconstitution therapy in NMOSD

Multiple Sclerosis and Related Disorders, 2021
NMO spectrum disorders [NMOSD] is a relapsing autoimmune disorder with attacks of optic neuritis (ON) and transverse myelitis (TM). A large proportion of NMOSD patients have no or a partial recovery after relapse.The neuro-immunological community now has a number of indicated agents for NMOSD therapy including eculizumab [SolirisĀ®], inebilizumab ...
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Immune reconstitution associated hypercalcemia

The American Journal of Emergency Medicine, 2009
The emergence of highly active antiretroviral therapy using combinations of reverse transcriptase and protease inhibitors ushered the dawn of a new era in management of human immunodeficiency virus infection. Immune reconstitution inflammatory syndrome is an adverse consequence of the restoration of pathogen-specific immune responses during the early ...
Yu-Tzu, Tsao   +3 more
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Immune reconstitution in HIV infection

Current Opinion in Immunology, 1997
Progressive immune deficiency arising during HIV disease reflects the continual degradation and the ultimate deletion of immune specificites defined by the CD4(+) T lymphocyte repertoire. Recent evidence suggests that improvements in the immune function of patients with HIV who receive therapy primarily reflects the expansion of CD4(+) T lymphocyte ...
Emery, S, Lane, HC
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Immune reconstitution following hematopoietic stem cell transplantation using different stem cell sources

Expert Review of Clinical Immunology, 2019
Introduction: Adequate immune reconstitution post-HSCT is crucial for the success of transplantation, and can be affected by both patient- and transplant-related factors.
R. Elfeky   +3 more
semanticscholar   +1 more source

Immune reconstitution strategies in HIV

Current Infectious Disease Reports, 2001
Although potent antiretroviral therapy can dramatically decrease HIV replication and improve some aspects of host immunity, incomplete immune reconstitution persists even after several years of fully suppressive therapy. In addition, long-term toxicities of antiretroviral medications and the probability of developing multidrug-resistant virus with long-
Matthew R., Leibowitz   +1 more
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Immune reconstitution of acquired immune deficiency syndrome

Chinese Journal of Integrative Medicine, 2010
Acquired immune deficiency syndrome (AIDS) is a chronic infectious disease, which the patients are infected with human immunodeficiency virus (HIV). HIV damages the human's immune function and causes CD4 cell decline in the number and function. Immune reconstitution is an important treatment to AIDS.
Jie, Wang   +3 more
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Growth Hormone in Immune Reconstitution

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1999
Immune cell death or dysfunction is induced by HIV infection and results in an immunocompromised state. Newer treatments are able to control viral replication to prevent massive cytoreduction. Attention must now focus on therapies that will rapidly reconstitute the immune system to provide defense against future HIV attacks as well as opportunistic ...
openaire   +2 more sources

Immune reconstitution syndrome and the thyroid

Best Practice & Research Clinical Endocrinology & Metabolism, 2009
Reconstitution Graves' disease occurs in three settings. First, bone marrow transplantation from a donor with Graves' disease may cause this disease to appear in the recipient, as a result of adoptive immunity, although disordered immunoregulation secondary to graft-versus-host disease may also play a role.
openaire   +2 more sources

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