Results 301 to 310 of about 2,306,505 (335)
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Immune reconstitution and remission in CML
Blood, 2017In a comprehensive and provocative report in this issue of Blood, with findings that were not necessarily expected, Hughes and colleagues report on the immune reconstitution that occurs as a consequence of the deepening remission achieved by patients with chronic myelogenous leukemia (CML) on tyrosine kinase inhibitors (TKIs). A significant fraction of
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Immune Reconstitution Inflammatory Syndrome
Emergency Medicine Clinics of North America, 2010Immune reconstitution inflammatory syndrome (IRIS) must be considered in the differential diagnosis for any patient infected with HIV who has begun ART in the preceding months. Distinguishing between manifestations of IRIS and active infection is of paramount importance and poses a diagnostic challenge to the provider in the acute care setting ...
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B cells in multiple sclerosis — from targeted depletion to immune reconstitution therapies
Nature Reviews Neurology, 2021M. T. Cencioni +4 more
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Immune Reconstitution in Patients with HIV Infection
Annual Review of Medicine, 2002▪ Abstract The peripheral T cell pool is damaged by HIV-1 infection and can be regenerated by production of new T lymphocytes either from the thymus or from proliferation of post-thymic T cells. A critical question for AIDS patients is whether treatment with antiretroviral drugs can restore the capability to produce new T lymphocytes.
Gregory D, Sempowski, Barton F, Haynes
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Best Practice & Research Clinical Haematology, 2004
Richard K Burt, Larissa Verda
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Richard K Burt, Larissa Verda
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Immunotherapy to reconstitute immunity to DNA viruses
Seminars in Hematology, 2002Defects in cytotoxic T-lymphocyte (CTL) function after hemopoietic stem cell transplantation (HSCT) are associated with an increased frequency and severity of viral diseases. Initial investigations of viral infections in immunosuppressed mice and subsequent clinical studies of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) in human stem cell ...
Benedikt, Gahn +3 more
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[Immune reconstitution syndrome].
Zeitschrift fur Rheumatologie, 2012The immune reconstitution inflammatory syndrome (IRIS) represents a heterogeneous group of conditions. Whilst they typically present in HIV-infected patients with advanced immunodeficiency, IRIS have also been described in HIV-negative patients with immune reconstitution due to other causes of immunosuppression.
D, Meyer-Olson, D, Ernst, M, Stoll
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Stem cells and immune reconstitution in AIDS
Blood Reviews, 2003The hematopoietic system generally has reserve sufficient to tolerate significant insult and regenerative capacity to overcome most damage due to infectious agents. However, HIV infection results in a progressive decline in hematopoietic function and even in the context of potent, anti-retroviral therapy is able to only incompletely reconstitute immune
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Immune reconstitution therapies: concepts for durable remission in multiple sclerosis
Nature Reviews Neurology, 2019J. Lünemann +4 more
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