Results 81 to 90 of about 2,934,852 (244)

Tuberculosis-immune reconstitution inflammatory syndrome in HIV-infected patient: A case report

IDCases, 2019
We describe a case of immune reconstitution inflammatory syndrome (IRIS) secondary to reactivation of Mycobacterium tuberculosis in an HIV-infected patient with a high CD4+ cell count, who presented with a generalized seizure 6 weeks after starting ...
Orel Shuker, Jose Villamil, Monica Ghitan, Edward K. Chapnick, Yu Shia Lin   +4 more
doaj   +1 more source

CD8+ T-cell encephalitis mimicking PRES in AIDS: a case report

BMC Neurology, 2020
Background Diverse mechanisms including infections, autoimmune inflammatory reactions, neoplasms, and degeneration are involved in the central nervous system in cases of acquired immune deficiency syndrome. In such cases, it is difficult to determine the
Mayu Ishiguro, Yuji Ueno, Yuta Ishiguro, Masashi Takanashi, Kenji Murai, Guillaume Taieb, Kensuke Daida, Akimitsu Suda, Kazumasa Yokoyama, Toshio Naito, Nobutaka Hattori   +10 more
doaj   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

Immune Reconstitution Inflammatory Syndrome Occurring in a Kidney Transplant Patient with Extrapulmonary Tuberculosis

Case Reports in Transplantation, 2017
Tuberculosis (TB) occurring in solid organ transplantation (SOT) is associated with significant morbidity and mortality usually due to delays in diagnosis, drug toxicity encountered with antimycobacterial therapy, and drug-drug interactions.
Jose Iglesias, Kandria Jumil Ledesma, Paul J. Couto, Jessie Liu   +3 more
doaj   +1 more source

The Epidemiology of IRIS in Southern India: An Observational Cohort Study

Journal of the International Association of Providers of AIDS Care, 2017
Immune reconstitution inflammatory syndrome (IRIS) is an uncommon but dynamic phenomenon seen among patients initiating antiretroviral therapy (ART). We aimed to describe incidence, risk factors, clinical spectrum, and outcomes among ART-naive patients ...
Nisha Thambuchetty MBBS, Kayur Mehta MD, Karthika Arumugam MSc, Umadevi G. Shekarappa MBBS, Jyothi Idiculla MD, MRCP, Anita Shet MD, PhD   +5 more
doaj   +1 more source

JC Polyomavirus, progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome: a review

AIDS Research and Therapy, 2020
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat, Yihong Zhou, Shengquan Tang, Yaokai Chen   +3 more
doaj   +1 more source

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Chylous Ascites in a Patient with HIV/AIDS: A Late Complication of Mycobacterium avium Complex-Immune Reconstitution Inflammatory Syndrome

Case Reports in Infectious Diseases, 2014
Chylous ascites is very rare in HIV/AIDS and its association with Mycobacterium avium complex-immune reconstitution inflammatory syndrome (MAC-IRIS) has been rarely reported.
Imam H. Shaik, Fernando Gonzalez-Ibarra, Rumana Khan, Saira Shah, Amer K. Syed, David Lintz   +5 more
doaj   +1 more source

Immune reconstitution inflammatory syndrome associated with pulmonary pathogens

European Respiratory Review, 2017
Immune reconstitution inflammatory syndrome (IRIS) is an exaggerated immune response to a variety of pathogens in response to antiretroviral therapy-mediated recovery of the immune system in HIV-infected patients.
Radha Gopal, Rekha R. Rapaka, Jay K. Kolls   +2 more
doaj   +1 more source