Results 191 to 200 of about 11,905,956 (387)

Endotoxin tolerance and trained immunity: breaking down immunological memory barriers

Frontiers in Immunology
For decades, innate immune cells were considered unsophisticated first responders, lacking the adaptive memory of their T and B cell counterparts. However, mounting evidence demonstrates the surprising complexity of innate immunity.
Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Carlos del Fresno, Carlos del Fresno   +4 more
doaj   +1 more source

Nature of the Immune Response to Mycoplasma Pneumoniae [PDF]

, 1967
Gerald W. Fernald, Wallace A. Clyde, Floyd W. Denny   +2 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Immune response in COVID-19: A review

Journal of Infection and Public Health, 2020
Mohammad Asaduzzaman Chowdhury, Nayem Hossain, M. A. Kashem, Md. Abdus Shahid, A. Alam   +4 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Prevalence of SARS-CoV-2 antibodies and associated factors in the adult population of Belgium: a general population cohort study between March 2021 and April 2022

Archives of Public Health
Background This study assessed seroprevalence trends of SARS-CoV-2 antibodies in the Belgian adult population between March 2021 and April 2022, and explored factors associated with seropositivity and seroreversion among the vaccinated and unvaccinated ...
Johan Van der Heyden, Victoria Leclercq, Els Duysburgh, Laura Cornelissen, Isabelle Desombere, Inge Roukaerts, Lydia Gisle   +6 more
doaj   +1 more source

Brevity of the Inductive Phase in the Immune Response of Mice to Capsular Polysaccharide Antigens [PDF]

, 1967
Phillip J. Baker, Maurice Landy
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Hallmarks of response, resistance, and toxicity to immune checkpoint blockade

Cell, 2021
Golnaz Morad, Beth A. Helmink, Padmanee Sharma, J. Wargo   +3 more
semanticscholar   +1 more source

Symposium on in vitro studies of the immune response. 3. Biochemical agents affecting the inductive phase of the secondary antibody respose initiated in vitro. [PDF]

, 1966
C T Ambrose
openalex   +1 more source