Results 191 to 200 of about 2,258,994 (317)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Quantitative systems pharmacology model of B cell immune response in mouse. [PDF]

Front Immunol
Ugolkov Y, Volkova A, Helmlinger G, Peskov K, Sokolov V.   +4 more
europepmc   +1 more source

[Form Q-10, Quarterly Report, June 30, 1994, the Immune Response Corporation]

, 1994
Immune Response Corporation
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

The role of pluripotency regulators in triple-negative breast cancer immune response. [PDF]

Front Genet
López-Santana C, Mendez-Rivera F, Bernal-Estévez DA.   +2 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Role of E5 from HPV16 in the Evasion of the Immune Response. [PDF]

Int J Mol Sci
Pérez-Morales AC, Maldonado-Gama M, Méndez-Armenta M, Esquivel-Guadarrama F, Gutierrez-Xicotencatl L.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evaluation of unipolar and bipolar nanosecond pulses for calcium electrochemotherapy and immune response. [PDF]

Front Immunol
Radzevičiūtė-Valčiukė E, Želvys A, Malyško V, Mickevičiūtė-Zinkuvienė E, Malakauskaitė P, Lekešytė B, Gečaitė J, Zinkevičienė A, Kašėta V, Kulbacka J, Rossowska J, Novickij V.   +11 more
europepmc   +1 more source

Immunization : Whose Responsibility?

Indian Journal of Community Medicine, 1987
Singh Bir, Lobo J, Pandav C.S, Kapoor S.K   +3 more
openaire   +2 more sources